股本结构
单位：万股
| 公告日期 | 2024-04-15 | 2024-02-20 | 2024-02-20 | 2023-11-02 | 2023-11-02 | 2023-08-03 |
|---|---|---|---|---|---|---|
| 证券总股本 | 3796.73 | 4258.62 | 4243.18 | 4242.15 | 4238.48 | 3671.48 |
| 普通股本 | 3796.73 | 4258.62 | 4243.18 | 4242.15 | 4238.48 | 3671.48 |
| 优先股 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 |
| 其他 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 |
| 变动日期 | 2024-04-08 | 2024-02-15 | 2023-12-31 | 2023-10-30 | 2023-09-30 | 2023-07-31 |
注释：中概股证券总股本=普通股股本/
存托凭证比例
，当前存托凭证比例为：1
历史变动
| 公告日期 | 变动后普通股本（万股） | 变动后优先股（万股） | 变动原因 | 变动日期 |
|---|---|---|---|---|
| 2024-04-15 | 3796.73 | 未披露 | 定期报告 | 2024-04-08 |
| 2024-02-20 | 4258.62 | 未披露 | 定期报告 | 2024-02-15 |
| 2024-02-20 | 4243.18 | 未披露 |
更多>>
From December 31, 2022 to December 31, 2023
Issuance of ADSs upon exercise of share options
Issuance of ADSs and non-voting ordinary shares, net of commissions and offering expenses of $16.0 million
Issuance of ADSs upon vesting of restricted share units
|
2023-12-31 |
| 2023-11-02 | 4242.15 | 未披露 | 定期报告 | 2023-10-30 |
| 2023-11-02 | 4238.48 | 未披露 |
更多>>
From June 30, 2023 to September 30, 2023
Issuance of ADSs and non-voting ordinary shares, net of commissions and offering expenses of $15.5 million
Issuance of ADSs upon vesting of restricted share units
Issuance of ADSs upon exercise of share options
|
2023-09-30 |
| 2023-08-03 | 3671.48 | 未披露 | 定期报告 | 2023-07-31 |
| 2023-07-20 | 3473.76 | 未披露 |
更多>>
ADSs offered 4,705,884 ADSs by the company,each representing one ordinary share.
|
2023-07-17 |
| 2023-08-03 | 3058.59 | 未披露 |
更多>>
From March 31, 2023 to June 30, 2023
Issuance of ADSs upon exercise of share options
Issuance of ADSs upon vesting of restricted share units
Issuance of ADSs, net of commissions and offering expenses of $0.4 million
|
2023-06-30 |
| 2023-04-28 | 3004.35 | 未披露 | 定期报告 | 2023-04-20 |
| 2023-05-04 | 3003.18 | 未披露 |
更多>>
From December 31, 2022 to March 31, 2023
Issuance of ADSs, net of commissions and offering expenses of $0.1 million
Issuance of ADSs upon vesting of restricted share units
Issuance of ADSs upon exercise of share options
|
2023-03-31 |
| 2023-02-28 | 3002.11 | 未披露 | 定期报告 | 2023-02-23 |
| 2023-02-28 | 2987.39 | 未披露 |
更多>>
From December 31, 2021 to December 31, 2022
Issuance of ADSs upon vesting of restricted share units
Issuance of ADSs upon exercise of share options
Issuance of ADSs, net of commissions and offering expenses of $0.2 million
|
2022-12-31 |
| 2022-11-03 | 2968.95 | 未披露 | 定期报告 | 2022-10-31 |
| 2022-11-03 | 2967.84 | 未披露 |
更多>>
From June 30, 2022 to September 30, 2022
Issuance of ADSs upon exercise of share options
|
2022-09-30 |
| 2022-08-04 | 2967.61 | 未披露 | 定期报告 | 2022-08-01 |
| 2022-08-04 | 2966.63 | 未披露 |
更多>>
From March 31, 2022 to June 30, 2022
Issuance of ADSs upon exercise of share options
|
2022-06-30 |
| 2022-05-05 | 2964.85 | 未披露 | 定期报告 | 2022-05-02 |
| 2022-04-29 | 2964.64 | 未披露 | 定期报告 | 2022-04-07 |
| 2022-05-05 | 2964.44 | 未披露 |
更多>>
From December 31, 2021 to March 31, 2022
Issuance of ADSs upon exercise of share options
Issuance of ADSs upon vesting of restricted share units
|
2022-03-31 |
| 2022-03-01 | 2959.86 | 未披露 | 定期报告 | 2022-02-24 |
| 2022-03-01 | 2957.94 | 未披露 |
更多>>
From December 31, 2020 to December 31, 2021
Issuance of ADSs upon exercise of share options
Issuance of ADSs, net of commissions and offering expenses of $16.1 million
Issuance of ordinary shares pursuant to the Ionis share purchase agreement
|
2021-12-31 |
| 2021-11-04 | 2939.97 | 未披露 | 定期报告 | 2021-11-01 |
| 2021-10-15 | 2736.53 | 未披露 |
更多>>
1.ADSs to be offered by company 3,240,741 ADSs.
2.The above discussion is based on 24,124,552 ordinary shares outstanding as of June 30, 2021.
|
2021-10-15 |
| 2021-11-04 | 2559.53 | 未披露 |
更多>>
From June 30, 2021 to September 30, 2021
Issuance of ADSs upon exercise of share options
Issuance of ADSs, net of commissions and offering expenses of $0.9 million
Issuance of ordinary shares pursuant to the Ionis share purchase agreement
|
2021-09-30 |
| 2021-08-05 | 2550.93 | 未披露 | 定期报告 | 2021-08-02 |
| 2021-08-05 | 2412.46 | 未披露 |
更多>>
From March 31, 2021 to June 30, 2021
Issuance of ADSs upon exercise of share options
Issuance of ADSs, net of commissions and offering expenses of $0.4 million
|
2021-06-30 |
| 2021-05-06 | 2407.77 | 未披露 | 定期报告 | 2021-05-03 |
| 2021-04-30 | 2402.80 | 未披露 | 定期报告 | 2021-04-23 |
| 2021-05-06 | 2351.66 | 未披露 |
更多>>
From December 31, 2020 to March 31, 2021
Issuance of ADSs upon exercise of share options
Issuance of ADSs, net of commissions and offering expenses of $1.8 million
|
2021-03-31 |
| 2021-03-11 | 2309.04 | 未披露 | 定期报告 | 2021-03-05 |
| 2021-03-11 | 2109.46 | 未披露 |
更多>>
From December 31, 2019 to December 31, 2020
Issuance of ordinary shares upon exercise of warrants
Issuance of ordinary shares upon exercise of share options
Issuance of ADSs, net of commissions and offering expenses of $1.9 million
|
2020-12-31 |
| 2020-11-05 | 2130.48 | 未披露 | 定期报告 | 2020-11-03 |
| 2020-11-05 | 2093.59 | 未披露 |
更多>>
From June 30, 2020 to September 30, 2020
Issuance of ordinary shares upon exercise of share options
Issuance of ADSs, net of commissions and offering expenses of $1.8 million
|
2020-09-30 |
| 2020-08-05 | 1928.44 | 未披露 | 定期报告 | 2020-08-03 |
| 2020-08-05 | 1809.17 | 未披露 |
更多>>
From March 31, 2020 to June 30, 2020
Issuance of ordinary shares upon exercise of share options
Issuance of ordinary shares upon exercise of warrants
|
2020-06-30 |
| 2020-04-27 | 1808.77 | 未披露 | 定期报告 | 2020-04-20 |
| 2020-05-07 | 1801.62 | 未披露 |
更多>>
From December 31, 2019 to March 31, 2020
Issuance of ordinary shares upon exercise of share options
Issuance of ordinary shares upon exercise of warrants
|
2020-03-31 |
| 2020-03-10 | 1799.48 | 未披露 | 定期报告 | 2020-03-05 |
| 2020-03-10 | 1799.37 | 未披露 |
更多>>
From December 31, 2018 to December 31, 2019
Conversion of convertible preferred shares to ordinary shares
Reclassification of warrant liability to additional paid-in capital and exercise of warrants
Issuance of ADSs in initial public offering, net of underwriting discounts, commissions and offering expenses of $8.5 million
Issuance of restricted share awards
Issuance of ordinary shares upon exercise of share options
|
2019-12-31 |
| 2019-11-07 | 1790.29 | 未披露 |
更多>>
from June 30, 2019 to September 30, 2019
Issuance of ordinary shares upon exercise of share options
|
2019-09-30 |
| 2019-08-08 | 1790.07 | 未披露 |
更多>>
From March 31, 2019 to June 30, 2019
Conversion of convertible preferred shares to ordinary shares
Reclassification of warrant liability to additional paid-in capital and exercise of warrants
Issuance of restricted share awards
Issuance of ordinary shares upon exercise of share options
Issuance of ADSs in initial public offering, net of underwriting discounts,commissions and offering expenses of $8.4 million
|
2019-06-30 |
| 2019-05-23 | 1769.64 | 未披露 |
更多>>
1.ADSs offered 4,333,333 ADSs
2.The number of ordinary shares to be outstanding after this offering is based on 898,678 ordinary shares (which includes 56,643 unvested restricted shares subject to repurchase by us) outstanding as of March 31, 2019
|
2019-05-23 |
| 2019-04-26 | 872.25 | 未披露 | 定期报告 | 2019-03-31 |
From December 31, 2022 to December 31, 2023
Issuance of ADSs upon exercise of share options
Issuance of ADSs and non-voting ordinary shares, net of commissions and offering expenses of $16.0 million
Issuance of ADSs upon vesting of restricted share units
From June 30, 2023 to September 30, 2023
Issuance of ADSs and non-voting ordinary shares, net of commissions and offering expenses of $15.5 million
Issuance of ADSs upon vesting of restricted share units
Issuance of ADSs upon exercise of share options
ADSs offered 4,705,884 ADSs by the company,each representing one ordinary share.
From March 31, 2023 to June 30, 2023
Issuance of ADSs upon exercise of share options
Issuance of ADSs upon vesting of restricted share units
Issuance of ADSs, net of commissions and offering expenses of $0.4 million
From December 31, 2022 to March 31, 2023
Issuance of ADSs, net of commissions and offering expenses of $0.1 million
Issuance of ADSs upon vesting of restricted share units
Issuance of ADSs upon exercise of share options
From December 31, 2021 to December 31, 2022
Issuance of ADSs upon vesting of restricted share units
Issuance of ADSs upon exercise of share options
Issuance of ADSs, net of commissions and offering expenses of $0.2 million
From June 30, 2022 to September 30, 2022
Issuance of ADSs upon exercise of share options
From March 31, 2022 to June 30, 2022
Issuance of ADSs upon exercise of share options
From December 31, 2021 to March 31, 2022
Issuance of ADSs upon exercise of share options
Issuance of ADSs upon vesting of restricted share units
From December 31, 2020 to December 31, 2021
Issuance of ADSs upon exercise of share options
Issuance of ADSs, net of commissions and offering expenses of $16.1 million
Issuance of ordinary shares pursuant to the Ionis share purchase agreement
1.ADSs to be offered by company 3,240,741 ADSs.
2.The above discussion is based on 24,124,552 ordinary shares outstanding as of June 30, 2021.
From June 30, 2021 to September 30, 2021
Issuance of ADSs upon exercise of share options
Issuance of ADSs, net of commissions and offering expenses of $0.9 million
Issuance of ordinary shares pursuant to the Ionis share purchase agreement
From March 31, 2021 to June 30, 2021
Issuance of ADSs upon exercise of share options
Issuance of ADSs, net of commissions and offering expenses of $0.4 million
From December 31, 2020 to March 31, 2021
Issuance of ADSs upon exercise of share options
Issuance of ADSs, net of commissions and offering expenses of $1.8 million
From December 31, 2019 to December 31, 2020
Issuance of ordinary shares upon exercise of warrants
Issuance of ordinary shares upon exercise of share options
Issuance of ADSs, net of commissions and offering expenses of $1.9 million
From June 30, 2020 to September 30, 2020
Issuance of ordinary shares upon exercise of share options
Issuance of ADSs, net of commissions and offering expenses of $1.8 million
From March 31, 2020 to June 30, 2020
Issuance of ordinary shares upon exercise of share options
Issuance of ordinary shares upon exercise of warrants
From December 31, 2019 to March 31, 2020
Issuance of ordinary shares upon exercise of share options
Issuance of ordinary shares upon exercise of warrants
From December 31, 2018 to December 31, 2019
Conversion of convertible preferred shares to ordinary shares
Reclassification of warrant liability to additional paid-in capital and exercise of warrants
Issuance of ADSs in initial public offering, net of underwriting discounts, commissions and offering expenses of $8.5 million
Issuance of restricted share awards
Issuance of ordinary shares upon exercise of share options
from June 30, 2019 to September 30, 2019
Issuance of ordinary shares upon exercise of share options
From March 31, 2019 to June 30, 2019
Conversion of convertible preferred shares to ordinary shares
Reclassification of warrant liability to additional paid-in capital and exercise of warrants
Issuance of restricted share awards
Issuance of ordinary shares upon exercise of share options
Issuance of ADSs in initial public offering, net of underwriting discounts,commissions and offering expenses of $8.4 million
1.ADSs offered 4,333,333 ADSs
2.The number of ordinary shares to be outstanding after this offering is based on 898,678 ordinary shares (which includes 56,643 unvested restricted shares subject to repurchase by us) outstanding as of March 31, 2019