股本结构
单位：万股
| 公告日期 | 2026-08-04 | 2026-08-04 | 2026-05-07 | 2026-04-17 | 2026-05-07 | 2026-02-24 |
|---|---|---|---|---|---|---|
| 证券总股本 | 10328.77 | 10326.46 | 10287.92 | 10274.57 | 10274.18 | 10185.62 |
| 普通股本 | 10328.77 | 10326.46 | 10287.92 | 10274.57 | 10274.18 | 10185.62 |
| 优先股 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 |
| 其他 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 |
| 变动日期 | 2026-07-28 | 2026-06-30 | 2026-04-30 | 2026-04-07 | 2026-03-31 | 2026-02-17 |
注释：中概股证券总股本=普通股股本/
存托凭证比例
历史变动
| 公告日期 | 变动后普通股本（万股） | 变动后优先股（万股） | 变动原因 | 变动日期 |
|---|---|---|---|---|
| 2026-08-04 | 10328.77 | 未披露 | 定期报告 | 2026-07-28 |
| 2026-08-04 | 10326.46 | 未披露 |
更多>>
From March 31,2026 to June 30,2026
Exercise of common stock options
Vesting of restricted common stock
|
2026-06-30 |
| 2026-05-07 | 10287.92 | 未披露 | 定期报告 | 2026-04-30 |
| 2026-04-17 | 10274.57 | 未披露 | 定期报告 | 2026-04-07 |
| 2026-05-07 | 10274.18 | 未披露 |
更多>>
From December 31, 2025 to March 31, 2026
Purchase of common stock under ESPP
Vesting of restricted common stock
Exercise of common stock options
|
2026-03-31 |
| 2026-02-24 | 10185.62 | 未披露 | 定期报告 | 2026-02-17 |
| 2026-02-24 | 10174.90 | 未披露 |
更多>>
From December 31, 2024 to December 31, 2025
Issuance of common stock and pre-funded warrants, net of issuance costs of $30.8 million
Purchase of common stock under ESPP
Vesting of restricted common stock
Issuance of common stock for acquisition
Exercise of common stock options
|
2025-12-31 |
| 2025-11-04 | 10147.49 | 未披露 | 定期报告 | 2025-10-28 |
| 2025-11-04 | 10135.98 | 未披露 |
更多>>
From June 30, 2025 to September 30, 2025
Purchase of common stock under ESPP
Vesting of restricted common stock
Issuance of common stock for acquisition
Exercise of common stock options
|
2025-09-30 |
| 2025-08-05 | 10116.20 | 未披露 | 定期报告 | 2025-07-29 |
| 2025-08-05 | 10075.87 | 未披露 |
更多>>
From March 31, 2025 to June 30, 2025
Vesting of restricted common stock
Exercise of common stock options
|
2025-06-30 |
| 2025-05-06 | 10055.71 | 未披露 |
更多>>
From December 31,2024 to March 31,2025
Purchase of common stock under ESPP
Issuance of common stock and pre-funded warrants, net of issuance costs of $30.8 million
Vesting of restricted common stock
Exercise of common stock options
|
2025-03-31 |
| 2025-03-10 | 9984.00 | 未披露 |
更多>>
Common stock offered 16,151,686 shares by the compsny
|
2025-03-11 |
| 2025-02-25 | 8368.83 | 未披露 | 定期报告 | 2025-02-18 |
| 2025-02-25 | 8363.31 | 未披露 |
更多>>
From December 31, 2023 to December 31, 2024
Exercise of common stock options
Purchase of common stock under ESPP
Vesting of restricted common stock
|
2024-12-31 |
| 2024-11-05 | 8280.56 | 未披露 | 定期报告 | 2024-10-29 |
| 2024-11-05 | 8255.89 | 未披露 |
更多>>
From June 30, 2024 to September 30, 2024
Purchase of common stock under ESPP
Vesting of restricted common stock
Exercise of common stock options
|
2024-09-30 |
| 2024-08-06 | 8241.56 | 未披露 | 定期报告 | 2024-07-31 |
| 2024-08-06 | 8238.62 | 未披露 |
更多>>
From March 31, 2024 to June 30, 2024
Exercise of common stock options
Vesting of restricted common stock
|
2024-06-30 |
| 2024-05-07 | 8231.11 | 未披露 | 定期报告 | 2024-04-30 |
| 2024-04-19 | 8231.02 | 未披露 | 定期报告 | 2024-04-09 |
| 2024-05-07 | 8228.08 | 未披露 |
更多>>
From December 31, 2023 to March 31, 2024
Vesting of restricted common stock
Purchase of common stock under ESPP
Exercise of common stock options
|
2024-03-31 |
| 2024-02-27 | 8165.77 | 未披露 | 定期报告 | 2024-02-20 |
| 2024-02-27 | 8163.25 | 未披露 |
更多>>
From December 31, 2022 to December 31, 2023
Issuance of common stock from At-the-Market offering, net of issuance costs of $6.1 million
Exercise of common stock options
Purchase of common stock under ESPP
Issuance of unregistered common shares in connection with license agreement
Vesting of restricted common stock
|
2023-12-31 |
| 2023-11-08 | 8150.41 | 未披露 | 定期报告 | 2023-11-01 |
| 2023-11-08 | 7938.20 | 未披露 |
更多>>
From June 30, 2023 to September 30, 2023
Issuance of common stock from At-the-Market offering, net of issuance costs of $0.8 million
Exercise of common stock options
Purchase of common stock under ESPP
Vesting of restricted common stock
|
2023-09-30 |
| 2023-08-08 | 7919.95 | 未披露 | 定期报告 | 2023-08-01 |
| 2023-08-08 | 7795.35 | 未披露 |
更多>>
From March 31, 2023 to June 30, 2023
Issuance of common stock from At-the-Market offering, net of issuance costs of $5.1 million
Vesting of restricted common stock
Exercise of common stock options
|
2023-06-30 |
| 2023-05-10 | 7621.75 | 未披露 | 定期报告 | 2023-05-03 |
| 2023-04-21 | 7467.53 | 未披露 | 定期报告 | 2023-04-10 |
| 2023-05-10 | 7443.54 | 未披露 |
更多>>
From December 31, 2022 to March 31, 2023
Issuance of common stock from At-the-Market offering, net of issuance costs of $0.2 million
Exercise of common stock options
Purchase of common stock under ESPP
Vesting of restricted common stock
|
2023-03-31 |
| 2023-02-28 | 7239.76 | 未披露 | 定期报告 | 2023-02-22 |
| 2023-02-28 | 7127.73 | 未披露 |
更多>>
From December 31, 2021 to December 31, 2022
Exercise of common stock options
Purchase of common stock under ESPP
Vesting of restricted common stock
Issuance of common stock from At-the-Market offering, net of issuance costs of $2.7 million
|
2022-12-31 |
| 2022-11-07 | 7046.90 | 未披露 | 定期报告 | 2022-10-31 |
| 2022-11-07 | 7045.77 | 未披露 |
更多>>
From June 30, 2022 to September 30, 2022
Purchase of common stock under ESPP
Vesting of restricted common stock
Exercise of common stock options
|
2022-09-30 |
| 2022-08-09 | 7035.46 | 未披露 | 定期报告 | 2022-08-02 |
| 2022-08-09 | 7031.21 | 未披露 |
更多>>
From March 31, 2022 to June 30, 2022
Issuance of common stock from At-the-Market offering, net of issuance costs of $0.6 million
Vesting of restricted common stock
Exercise of common stock options
|
2022-06-30 |
| 2022-05-09 | 7026.68 | 未披露 | 定期报告 | 2022-05-02 |
| 2022-04-22 | 7016.97 | 未披露 | 定期报告 | 2022-04-11 |
| 2022-05-09 | 6975.30 | 未披露 |
更多>>
From December 31, 2021 to March 31, 2022
Purchase of common stock under ESPP
Issuance of common stock from At-the-Market offering, net of issuance costs of $1.3 million
Vesting of restricted common stock
Other comprehensive income
|
2022-03-31 |
| 2022-02-28 | 6873.03 | 未披露 | 定期报告 | 2022-02-22 |
| 2022-02-28 | 6838.94 | 未披露 |
更多>>
From December 31, 2020 to December 31, 2021
Issuance of common stock from private placement, net of issuance costs of $8.0 million
Issuance of common stock from At-the-Market offering, net of issuance costs of $14.6 million
Issuance of common stock for success payment liability
Issuance of common stock to acquire Guide
Vesting of restricted common stock
Exercise of common stock options
|
2021-12-31 |
| 2021-11-08 | 6813.58 | 未披露 | 定期报告 | 2021-11-01 |
| 2021-11-08 | 6773.45 | 未披露 |
更多>>
From June 30, 2021 to September 30, 2021
Issuance of common stock from At-the-Market offering, net of issuance costs of $8.6 million
Vesting of restricted common stock
Exercise of common stock options
|
2021-09-30 |
| 2021-08-10 | 6635.07 | 未披露 | 定期报告 | 2021-08-03 |
| 2021-08-10 | 6445.27 | 未披露 |
更多>>
From March 31, 2021 to June 30, 2021
Issuance of common stock from At-the-Market offering, net of issuance costs of $5.5 million
Vesting of restricted common stock
Issuance of common stock for success payment liability
Exercise of common stock options
|
2021-06-30 |
| 2021-05-11 | 6257.81 | 未披露 | 定期报告 | 2021-05-04 |
| 2021-04-23 | 6253.85 | 未披露 | 定期报告 | 2021-04-12 |
| 2021-05-11 | 6173.51 | 未披露 |
更多>>
From December 31, 2020 to March 31, 2021
Issuance of common stock from private placement, net of issuance costs of $8.0 million
Issuance of common stock to acquire Guide
Vesting of restricted common stock
Exercise of common stock options
|
2021-03-31 |
| 2021-04-01 | 6247.02 | 未披露 | 定期报告 | 2021-03-15 |
| 2021-03-15 | 6241.55 | 未披露 | 定期报告 | 2021-03-08 |
| 2021-03-15 | 5725.42 | 未披露 |
更多>>
From December 31, 2019 to December 31, 2020
Conversion of redeemable convertible preferred stock to common stock upon closing of initial public offering
Issuance of common stock from initial public offering, net of issuance costs of $18.7 million
Issuance of common stock from October 2020 public offering, net of issuance costs of $8.5 million
Issuance of common stock related to license agreements
Vesting of restricted common stock
Exercise of common stock options
|
2020-12-31 |
| 2020-11-10 | 5796.60 | 未披露 | 定期报告 | 2020-11-06 |
| 2020-10-05 | 5652.58 | 未披露 |
更多>>
1.Common stock offered by the company 5,000,000 shares.
2.The number of shares of common stock to be outstanding following this offering is based on 51,525,807 shares of common stock outstanding as of June 30, 2020, which includes 1,880,070 shares of unvested restricted stock.
|
2020-10-05 |
| 2020-11-10 | 5043.87 | 未披露 |
更多>>
From June 30, 2020 to September 30, 2020
Vesting of restricted common stock
Issuance of common stock related to license agreement
Exercise of common stock options
|
2020-09-30 |
| 2020-09-28 | 5014.26 | 未披露 | 定期报告 | 2020-08-31 |
| 2020-08-12 | 5173.20 | 未披露 | 定期报告 | 2020-08-04 |
| 2020-08-12 | 4964.57 | 未披露 |
更多>>
From March 31, 2020 to June 30, 2020
Vesting of restricted common stock
Exercise of common stock options
|
2020-06-30 |
| 2020-05-12 | 5148.51 | 未披露 | 定期报告 | 2020-05-08 |
| 2020-05-12 | 4907.74 | 未披露 |
更多>>
From December 31, 2019 to March 31, 2020
Conversion of redeemable convertible preferred stock to common stock upon closing of initial public offering
Issuance of common stock from initial public offering, net of issuance costs of $18.7 million
Vesting of restricted common stock
Exercise of common stock options
|
2020-03-31 |
| 2020-03-30 | 5133.97 | 未披露 | 定期报告 | 2020-03-25 |
| 2020-02-07 | 4966.31 | 未披露 |
更多>>
1.Common stock offered by us 10,588,236 shares.
2.The number of shares of common stock to be outstanding following this offering is based on 39,074,846 shares of common stock outstanding as of September 30, 2019
|
2020-02-06 |
From March 31,2026 to June 30,2026
Exercise of common stock options
Vesting of restricted common stock
From December 31, 2025 to March 31, 2026
Purchase of common stock under ESPP
Vesting of restricted common stock
Exercise of common stock options
From December 31, 2024 to December 31, 2025
Issuance of common stock and pre-funded warrants, net of issuance costs of $30.8 million
Purchase of common stock under ESPP
Vesting of restricted common stock
Issuance of common stock for acquisition
Exercise of common stock options
From June 30, 2025 to September 30, 2025
Purchase of common stock under ESPP
Vesting of restricted common stock
Issuance of common stock for acquisition
Exercise of common stock options
From March 31, 2025 to June 30, 2025
Vesting of restricted common stock
Exercise of common stock options
From December 31,2024 to March 31,2025
Purchase of common stock under ESPP
Issuance of common stock and pre-funded warrants, net of issuance costs of $30.8 million
Vesting of restricted common stock
Exercise of common stock options
Common stock offered 16,151,686 shares by the compsny
From December 31, 2023 to December 31, 2024
Exercise of common stock options
Purchase of common stock under ESPP
Vesting of restricted common stock
From June 30, 2024 to September 30, 2024
Purchase of common stock under ESPP
Vesting of restricted common stock
Exercise of common stock options
From March 31, 2024 to June 30, 2024
Exercise of common stock options
Vesting of restricted common stock
From December 31, 2023 to March 31, 2024
Vesting of restricted common stock
Purchase of common stock under ESPP
Exercise of common stock options
From December 31, 2022 to December 31, 2023
Issuance of common stock from At-the-Market offering, net of issuance costs of $6.1 million
Exercise of common stock options
Purchase of common stock under ESPP
Issuance of unregistered common shares in connection with license agreement
Vesting of restricted common stock
From June 30, 2023 to September 30, 2023
Issuance of common stock from At-the-Market offering, net of issuance costs of $0.8 million
Exercise of common stock options
Purchase of common stock under ESPP
Vesting of restricted common stock
From March 31, 2023 to June 30, 2023
Issuance of common stock from At-the-Market offering, net of issuance costs of $5.1 million
Vesting of restricted common stock
Exercise of common stock options
From December 31, 2022 to March 31, 2023
Issuance of common stock from At-the-Market offering, net of issuance costs of $0.2 million
Exercise of common stock options
Purchase of common stock under ESPP
Vesting of restricted common stock
From December 31, 2021 to December 31, 2022
Exercise of common stock options
Purchase of common stock under ESPP
Vesting of restricted common stock
Issuance of common stock from At-the-Market offering, net of issuance costs of $2.7 million
From June 30, 2022 to September 30, 2022
Purchase of common stock under ESPP
Vesting of restricted common stock
Exercise of common stock options
From March 31, 2022 to June 30, 2022
Issuance of common stock from At-the-Market offering, net of issuance costs of $0.6 million
Vesting of restricted common stock
Exercise of common stock options
From December 31, 2021 to March 31, 2022
Purchase of common stock under ESPP
Issuance of common stock from At-the-Market offering, net of issuance costs of $1.3 million
Vesting of restricted common stock
Other comprehensive income
From December 31, 2020 to December 31, 2021
Issuance of common stock from private placement, net of issuance costs of $8.0 million
Issuance of common stock from At-the-Market offering, net of issuance costs of $14.6 million
Issuance of common stock for success payment liability
Issuance of common stock to acquire Guide
Vesting of restricted common stock
Exercise of common stock options
From June 30, 2021 to September 30, 2021
Issuance of common stock from At-the-Market offering, net of issuance costs of $8.6 million
Vesting of restricted common stock
Exercise of common stock options
From March 31, 2021 to June 30, 2021
Issuance of common stock from At-the-Market offering, net of issuance costs of $5.5 million
Vesting of restricted common stock
Issuance of common stock for success payment liability
Exercise of common stock options
From December 31, 2020 to March 31, 2021
Issuance of common stock from private placement, net of issuance costs of $8.0 million
Issuance of common stock to acquire Guide
Vesting of restricted common stock
Exercise of common stock options
From December 31, 2019 to December 31, 2020
Conversion of redeemable convertible preferred stock to common stock upon closing of initial public offering
Issuance of common stock from initial public offering, net of issuance costs of $18.7 million
Issuance of common stock from October 2020 public offering, net of issuance costs of $8.5 million
Issuance of common stock related to license agreements
Vesting of restricted common stock
Exercise of common stock options
1.Common stock offered by the company 5,000,000 shares.
2.The number of shares of common stock to be outstanding following this offering is based on 51,525,807 shares of common stock outstanding as of June 30, 2020, which includes 1,880,070 shares of unvested restricted stock.
From June 30, 2020 to September 30, 2020
Vesting of restricted common stock
Issuance of common stock related to license agreement
Exercise of common stock options
From March 31, 2020 to June 30, 2020
Vesting of restricted common stock
Exercise of common stock options
From December 31, 2019 to March 31, 2020
Conversion of redeemable convertible preferred stock to common stock upon closing of initial public offering
Issuance of common stock from initial public offering, net of issuance costs of $18.7 million
Vesting of restricted common stock
Exercise of common stock options
1.Common stock offered by us 10,588,236 shares.
2.The number of shares of common stock to be outstanding following this offering is based on 39,074,846 shares of common stock outstanding as of September 30, 2019