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股本结构

单位：万股
公告日期 2024-04-22 2024-04-22 2024-03-04 2024-04-22 2023-11-02 2023-11-02
证券总股本 456.18 9123.50 9061.90 9060.20 9043.38 9041.59
普通股本 456.18 9123.50 9061.90 9060.20 9043.38 9041.59
优先股 未披露 未披露 未披露 210.45 未披露 210.45
其他 未披露 未披露 未披露 未披露 未披露 未披露
变动日期 2024-04-24 2024-04-12 2024-02-27 2023-12-31 2023-10-31 2023-09-30
注释：中概股证券总股本=普通股股本/ 存托凭证比例

历史变动

公告日期 变动后普通股本（万股） 变动后优先股（万股） 变动原因 变动日期
2024-04-22 456.18 未披露
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On April 12, 2024, the Company’s board of directors approved a reverse stock split of the Company’s common stock at a ratio of 1-for-20.
2024-04-24
2024-04-22 9123.50 未披露 定期报告 2024-04-12
2024-03-04 9061.90 未披露 定期报告 2024-02-27
2024-04-22 9060.20 210.45
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From December 31, 2022 to December 31, 2023 Issuance of common stock for exercise of stock options Public offering of common stock, net of issuance costs Issuance of common stock under Employee Stock Purchase Plan Underwritten public offering, net of issuance costs Issuance of common stock for restricted share units vested
2023-12-31
2023-11-02 9043.38 未披露 定期报告 2023-10-31
2023-11-02 9041.59 210.45
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From June 30, 2023 to September 30, 2023 Issuance of common stock for restricted share units vested
2023-09-30
2023-08-03 9025.17 210.45
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From March 31, 2023 to June 30, 2023 Public offering of common stock, net of issuance costs Issuance of common stock under Employee Stock Purchase Plan Issuance of common stock for restricted share units vested
2023-06-30
2023-05-11 9002.52 未披露 定期报告 2023-05-08
2023-04-27 9002.48 未披露 定期报告 2023-04-25
2023-05-11 9002.46 210.45
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From December 31, 2022 to March 31, 2023 Underwritten public offering, net of issuance costs Public offering of common stock, net of issuance costs Issuance of common stock for exercise of options Issuance of common stock for restricted share units vested
2023-03-31
2023-03-23 8900.84 未披露 定期报告 2023-03-16
2023-03-06 8125.81 未披露
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Common stock offered 9,640,000 shares by the company
2023-03-07
2023-03-23 7247.04 187.07
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From December 31, 2021 to December 31, 2022 Issuance of common stock for restricted share units vested Issuance of common stock under Employee Stock Purchase Plan Public offering of common stock, net of issuance costs
2022-12-31
2022-11-03 7161.81 未披露 定期报告 2022-10-31
2022-11-03 7118.12 187.07
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From June 30, 2022 to September 30, 2022 Issuance of common stock for restricted share units vested Public offering of common stock, net of issuance costs
2022-09-30
2022-08-09 7007.57 未披露 定期报告 2022-07-29
2022-08-09 6923.85 187.07
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From March 31, 2022 to June 30, 2022 Issuance of common stock for restricted share units vested Issuance of common stock under Employee Stock Purchase Plan
2022-06-30
2022-04-29 6904.95 未披露 定期报告 2022-04-25
2022-05-11 6904.92 187.07
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From December 31, 2021 to March 31, 2022 Public offering of common stock, net of issuance costs Issuance of common stock for restricted share units vested
2022-03-31
2022-03-07 6815.46 未披露 定期报告 2022-02-28
2022-03-07 6786.37 181.85
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From December 31, 2020 to December 31, 2021 Underwritten public offering, net of issuance costs Public offering of common stock, net of issuance costs Issuance of common stock for exercise of stock options Issuance of common stock for restricted share units vested Issuance of common stock under Employee Stock Purchase Plan
2021-12-31
2021-11-10 6668.61 未披露 定期报告 2021-10-29
2021-10-13 7208.69 未披露
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1.Common stock offered 14,838,706 shares. 2.The number of shares of common stock to be outstanding immediately after the offering is based on 49,506,268 shares of common stock outstanding as of June 30, 2021.
2021-10-13
2021-11-10 4962.15 109.65 定期报告 2021-09-30
2021-08-12 4950.63 109.65
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From March 31, 2021 to June 30, 2021 Public offering of common stock, net of issuance costs Issuance of common stock for exercise of options Issuance of common stock for restricted share units vested Issuance of common stock under Employee Stock Purchase Plan
2021-06-30
2021-04-28 4828.98 未披露 定期报告 2021-04-26
2021-05-13 4828.87 109.65
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From December 31, 2020 to March 31, 2021 Public offering of common stock, net of issuance costs Issuance of common stock for exercise of options Issuance of common stock for restricted share units vested
2021-03-31
2021-02-25 4804.31 未披露 定期报告 2021-02-18
2021-02-25 4487.64 104.43
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From December 31, 2019 to December 31, 2020 Rights offering, net of offering costs Public offering of common stock, net of issuance costs Issuance of common stock upon conversion of Series X Convertible Preferred Stock Issuance of common stock for exercise of stock options Issuance of common stock for restricted share units vested Issuance of common stock under Employee Stock Purchase Plan
2020-12-31
2020-11-05 4393.79 未披露 定期报告 2020-10-31
2020-11-05 4393.60 104.43
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From June 30, 2020 to September 30, 2020 Issuance of common stock, net of offering costs Issuance of common stock upon conversion of Series X Convertible Preferred Stock Issuance of common stock for exercise of options Issuance of common stock for restricted share units vested
2020-09-30
2020-08-13 4295.92 未披露 定期报告 2020-07-31
2020-08-13 4201.92 109.65
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From March 31, 2020 to June 30, 2020 Issuance of common stock, net of offering costs Issuance of common stock under Employee Stock Purchase Plan
2020-06-30
2020-06-05 4111.62 未披露 定期报告 2020-06-04
2020-05-13 4074.65 未披露 定期报告 2020-04-30
2020-04-29 4073.65 未披露 定期报告 2020-04-27
2020-05-13 4055.95 109.65
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From December 31, 2019 to March 31, 2020 Rights offering, net of offering costs Issuance of common stock, net of offering costs Issuance of common stock for exercise of options Issuance of common stock for restricted share units vested
2020-03-31
2020-03-04 4051.36 未披露 定期报告 2020-02-25
2020-01-22 3387.43 56.52 定期报告 2020-01-21
2020-03-04 3383.85 56.52
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from December 31, 2018 to December 31, 2019 Issuance of common stock for restricted share units vested Issuance of common stock for exercise of options Issuance of common stock under Employee Stock Purchase Plan Issuance of Series X Convertible Preferred Stock in exchange for common stock Public offering of common stock, net of issuance costs Issuance of stock pursuant to Stock Purchase Agreement
2019-12-31
2019-11-08 3304.03 未披露 定期报告 2019-10-31
2019-11-08 3300.63 56.52
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From June 30, 2019 to September 30, 2019 Vesting of restricted stock units Issuance of common stock pursuant to Stock Purchase Agreement Sale of common stock, net of issuance costs
2019-09-30
2019-08-08 2676.80 56.52
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From March 31, 2019 to June 30, 2019 Issuance of common stock under Employee Stock Purchase Plan
2019-06-30
2019-05-09 2664.19 56.52
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from December 31, 2018 to March 31, 2019 Issuance of Series X preferred stock in exchange for common stock Vesting of restricted stock units
2019-03-31
2019-02-28 2781.60 44.52
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From December 31, 2017 to December 31, 2018 Registered Direct Offering, net of offering costs Public offering of common stock, net of issuance costs Vesting of restricted shares Issuance of common stock for exercise of stock options Issuance of common stock under Employee Stock Purchase Plan
2018-12-31
2018-11-08 2775.14 未披露 定期报告 2018-10-31
2018-11-08 2775.14 44.52 定期报告 2018-09-30
2018-08-09 2767.95 未披露 定期报告 2018-07-31
2018-08-09 2767.82 44.52 定期报告 2018-06-30
2018-06-21 2767.82 未披露 定期报告 2018-06-15
2018-05-10 2139.11 未披露 定期报告 2018-04-30
2018-04-27 2139.51 未披露 定期报告 2018-04-18
2018-05-10 2138.97 未披露 定期报告 2018-03-31
2018-02-27 2077.12 未披露 定期报告 2018-02-20
2018-02-27 2052.57 未披露
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from December 31, 2016 to December 31, 2017 Sale of common stock, net of issuance costs Vesting of restricted shares Issuance of common stock for exercise of stock options Issuance of common stock for restricted share units vested Issuance of common stock under Employee Stock Purchase Plan
2017-12-31
2017-11-08 2023.81 未披露 定期报告 2017-10-31
2017-11-08 1686.57 未披露 定期报告 2017-09-30
2017-08-09 1686.31 未披露 定期报告 2017-07-31
2017-08-09 1686.08 未披露 定期报告 2017-06-30
2017-05-10 1680.60 未披露 定期报告 2017-04-30
2017-04-28 1682.59 未披露 定期报告 2017-04-25
2017-05-10 1680.47 未披露 定期报告 2017-03-31
2017-03-15 1680.12 未披露 定期报告 2017-02-28
2017-03-15 1677.32 未披露
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from December 31, 2015 to December 31, 2016 Public offering of common stock, net of issuance costs Vesting of restricted shares Issuance of common stock for exercise of stock options Issuance of common stock under Employee Stock Purchase Plan
2016-12-31
2016-11-10 1667.33 未披露 定期报告 2016-10-31
2016-11-10 1391.60 未披露 定期报告 2016-09-30
2016-08-11 1390.67 未披露 定期报告 2016-07-31
2016-08-11 1390.06 未披露 定期报告 2016-06-30
2016-05-12 1385.48 未披露 定期报告 2016-04-30
2016-04-29 1396.27 未披露 定期报告 2016-04-25
2016-05-12 1383.98 未披露 定期报告 2016-03-31
2016-03-18 1382.27 未披露 定期报告 2016-02-29
2016-03-18 1378.63 未披露
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from December 31, 2014 to December 31, 2015 Issuance of Series B convertible preferred stock, net of issuance costs of $99 Conversion of Series A and Series B convertible preferred upon initial public offering Public offering of common stock, net of issuance costs Issuance of common stock under employee stock purchase plan Vesting of restricted shares Issuance of common stock for exercise of stock options On April 2, 2015, the Company’s board of directors and stockholders approved a 1-for-25.4 reverse stock split of its outstanding common stock.
2015-12-31
2015-11-16 1371.97 未披露 定期报告 2015-11-10
2015-11-16 1369.63 未披露 定期报告 2015-09-30
2015-08-11 1367.43 未披露 定期报告 2015-08-10
2015-08-11 1359.87 未披露 定期报告 2015-06-30
2015-05-21 1351.09 未披露
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On April 2, 2015, the Company’s board of directors and stockholders approved a 1-for-25.4 reverse stock split of its outstanding common stock. The reverse stock split resulted in an adjustment to the conversion prices of the Series A preferred and Series B preferred to reflect a proportional decrease in the number of shares of common stock to be issued upon conversion, which occurred in connection with the closing of the Company’s IPO. The accompanying financial statements and notes to the financial statements give retroactive effect to the reverse stock split for all periods presented.
2015-05-18
2015-04-15 1349.41 未披露 定期报告 2015-04-15
2015-05-21 114.71 19205.93 定期报告 2015-03-31
2015-04-06 113.27 9752.61
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From December 31, 2013 to December 31, 2014 Issuance of Series A convertible preferred stock, net of issuance costs of $159 Issuance of Series A convertible preferred stock upon conversion of convertible notes payable Issuance of common stock for in-process research and development Vesting of restricted shares Issuance of common stock for exercise of options
2014-12-31
On April 12, 2024, the Company’s board of directors approved a reverse stock split of the Company’s common stock at a ratio of 1-for-20.
From December 31, 2022 to December 31, 2023 Issuance of common stock for exercise of stock options Public offering of common stock, net of issuance costs Issuance of common stock under Employee Stock Purchase Plan Underwritten public offering, net of issuance costs Issuance of common stock for restricted share units vested
From June 30, 2023 to September 30, 2023 Issuance of common stock for restricted share units vested
From March 31, 2023 to June 30, 2023 Public offering of common stock, net of issuance costs Issuance of common stock under Employee Stock Purchase Plan Issuance of common stock for restricted share units vested
From December 31, 2022 to March 31, 2023 Underwritten public offering, net of issuance costs Public offering of common stock, net of issuance costs Issuance of common stock for exercise of options Issuance of common stock for restricted share units vested
Common stock offered 9,640,000 shares by the company
From December 31, 2021 to December 31, 2022 Issuance of common stock for restricted share units vested Issuance of common stock under Employee Stock Purchase Plan Public offering of common stock, net of issuance costs
From June 30, 2022 to September 30, 2022 Issuance of common stock for restricted share units vested Public offering of common stock, net of issuance costs
From March 31, 2022 to June 30, 2022 Issuance of common stock for restricted share units vested Issuance of common stock under Employee Stock Purchase Plan
From December 31, 2021 to March 31, 2022 Public offering of common stock, net of issuance costs Issuance of common stock for restricted share units vested
From December 31, 2020 to December 31, 2021 Underwritten public offering, net of issuance costs Public offering of common stock, net of issuance costs Issuance of common stock for exercise of stock options Issuance of common stock for restricted share units vested Issuance of common stock under Employee Stock Purchase Plan
1.Common stock offered 14,838,706 shares. 2.The number of shares of common stock to be outstanding immediately after the offering is based on 49,506,268 shares of common stock outstanding as of June 30, 2021.
From March 31, 2021 to June 30, 2021 Public offering of common stock, net of issuance costs Issuance of common stock for exercise of options Issuance of common stock for restricted share units vested Issuance of common stock under Employee Stock Purchase Plan
From December 31, 2020 to March 31, 2021 Public offering of common stock, net of issuance costs Issuance of common stock for exercise of options Issuance of common stock for restricted share units vested
From December 31, 2019 to December 31, 2020 Rights offering, net of offering costs Public offering of common stock, net of issuance costs Issuance of common stock upon conversion of Series X Convertible Preferred Stock Issuance of common stock for exercise of stock options Issuance of common stock for restricted share units vested Issuance of common stock under Employee Stock Purchase Plan
From June 30, 2020 to September 30, 2020 Issuance of common stock, net of offering costs Issuance of common stock upon conversion of Series X Convertible Preferred Stock Issuance of common stock for exercise of options Issuance of common stock for restricted share units vested
From March 31, 2020 to June 30, 2020 Issuance of common stock, net of offering costs Issuance of common stock under Employee Stock Purchase Plan
From December 31, 2019 to March 31, 2020 Rights offering, net of offering costs Issuance of common stock, net of offering costs Issuance of common stock for exercise of options Issuance of common stock for restricted share units vested
from December 31, 2018 to December 31, 2019 Issuance of common stock for restricted share units vested Issuance of common stock for exercise of options Issuance of common stock under Employee Stock Purchase Plan Issuance of Series X Convertible Preferred Stock in exchange for common stock Public offering of common stock, net of issuance costs Issuance of stock pursuant to Stock Purchase Agreement
From June 30, 2019 to September 30, 2019 Vesting of restricted stock units Issuance of common stock pursuant to Stock Purchase Agreement Sale of common stock, net of issuance costs
From March 31, 2019 to June 30, 2019 Issuance of common stock under Employee Stock Purchase Plan
from December 31, 2018 to March 31, 2019 Issuance of Series X preferred stock in exchange for common stock Vesting of restricted stock units
From December 31, 2017 to December 31, 2018 Registered Direct Offering, net of offering costs Public offering of common stock, net of issuance costs Vesting of restricted shares Issuance of common stock for exercise of stock options Issuance of common stock under Employee Stock Purchase Plan
from December 31, 2016 to December 31, 2017 Sale of common stock, net of issuance costs Vesting of restricted shares Issuance of common stock for exercise of stock options Issuance of common stock for restricted share units vested Issuance of common stock under Employee Stock Purchase Plan
from December 31, 2015 to December 31, 2016 Public offering of common stock, net of issuance costs Vesting of restricted shares Issuance of common stock for exercise of stock options Issuance of common stock under Employee Stock Purchase Plan
from December 31, 2014 to December 31, 2015 Issuance of Series B convertible preferred stock, net of issuance costs of $99 Conversion of Series A and Series B convertible preferred upon initial public offering Public offering of common stock, net of issuance costs Issuance of common stock under employee stock purchase plan Vesting of restricted shares Issuance of common stock for exercise of stock options On April 2, 2015, the Company’s board of directors and stockholders approved a 1-for-25.4 reverse stock split of its outstanding common stock.
On April 2, 2015, the Company’s board of directors and stockholders approved a 1-for-25.4 reverse stock split of its outstanding common stock. The reverse stock split resulted in an adjustment to the conversion prices of the Series A preferred and Series B preferred to reflect a proportional decrease in the number of shares of common stock to be issued upon conversion, which occurred in connection with the closing of the Company’s IPO. The accompanying financial statements and notes to the financial statements give retroactive effect to the reverse stock split for all periods presented.
From December 31, 2013 to December 31, 2014 Issuance of Series A convertible preferred stock, net of issuance costs of $159 Issuance of Series A convertible preferred stock upon conversion of convertible notes payable Issuance of common stock for in-process research and development Vesting of restricted shares Issuance of common stock for exercise of options