股本结构
单位：万股
| 公告日期 | 2022-11-07 | 2022-11-07 | 2022-08-04 | 2022-08-04 | 2022-06-06 | 2022-05-05 |
|---|---|---|---|---|---|---|
| 证券总股本 | 4793.82 | 4793.46 | 4793.46 | 4792.44 | 4495.33 | 3495.33 |
| 普通股本 | 4793.82 | 4793.46 | 4793.46 | 4792.44 | 4495.33 | 3495.33 |
| 优先股 | 未披露 | 2.07 | 未披露 | 1.66 | 未披露 | 未披露 |
| 其他 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 |
| 变动日期 | 2022-11-01 | 2022-09-30 | 2022-08-01 | 2022-06-30 | 2022-06-06 | 2022-03-31 |
注释：中概股证券总股本=普通股股本/
存托凭证比例
历史变动
| 公告日期 | 变动后普通股本（万股） | 变动后优先股（万股） | 变动原因 | 变动日期 |
|---|---|---|---|---|
| 2022-11-07 | 4793.82 | 未披露 | 定期报告 | 2022-11-01 |
| 2022-11-07 | 4793.46 | 2.07 |
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From June 30, 2022 to September 30, 2022
Exercise of warrants
|
2022-09-30 |
| 2022-08-04 | 4793.46 | 未披露 | 定期报告 | 2022-08-01 |
| 2022-08-04 | 4792.44 | 1.66 |
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From March 31, 2022 to June 30, 2022
Release of restricted stock units
Conversion of preferred stock
Exercise of warrants
Sale of common stock, net of underwriters' discount and costs
|
2022-06-30 |
| 2022-06-06 | 4495.33 | 未披露 |
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1.Common stock offered by 10,000,000 shares.
2.The number of shares of common stock to be outstanding after this offering is based on the 34,953,342 shares of common stock outstanding as of March 31, 2022.
|
2022-06-06 |
| 2022-04-14 | 3632.93 | 未披露 | 定期报告 | 2022-04-12 |
| 2022-05-05 | 3495.33 | 1.40 |
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From December 31, 2021 to March 31, 2022
Release of restricted stock units
|
2022-03-31 |
| 2022-03-03 | 3495.33 | 未披露 | 定期报告 | 2022-02-28 |
| 2022-03-03 | 3473.90 | 1.40 |
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From December 31, 2020 to December 31, 2021
Exercise of stock options
Release of restricted stock units
Proceeds from at-the-market offering, net of issuance costs
Sale of common and preferred stock, warrants and royalty interest (2021 Financing), net of issuance costs
|
2021-12-31 |
| 2021-11-05 | 3465.98 | 未披露 |
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1.Common stock to be offered 2,253,000 shares.
2.The above discussion is based on 32,173,778 shares of common stock outstanding as of June 30, 2021.
|
2021-11-05 |
| 2021-11-09 | 3240.68 | 未披露 |
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From June 30, 2021 to September 30, 2021
Release of restricted stock units
|
2021-09-30 |
| 2021-05-04 | 3217.38 | 未披露 |
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from December 31, 2020 to March 31, 2021
Exercise of stock options
Release of restricted stock units
Proceeds from at-the-market offering, net of issuance costs
|
2021-03-31 |
| 2021-02-25 | 3217.38 | 未披露 | 定期报告 | 2021-02-19 |
| 2021-02-25 | 3186.22 | 未披露 |
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From December 31, 2019 to December 31, 2020
Exercise of stock options
Release of restricted stock units
Sale of common stock and pre-funded warrants, net of underwriters' discount and costs
Proceeds from at-the-market offering, net of issuance costs
|
2020-12-31 |
| 2020-11-05 | 3064.92 | 未披露 | 定期报告 | 2020-10-30 |
| 2020-11-05 | 2981.80 | 未披露 |
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From June 30, 2020 to September 30, 2020
Exercise of stock options
Release of restricted stock units
|
2020-09-30 |
| 2020-08-06 | 2967.81 | 未披露 |
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From March 31, 2020 to June 30, 2020
Exercise of stock options
|
2020-06-30 |
| 2020-04-30 | 2965.33 | 未披露 | 定期报告 | 2020-04-24 |
| 2020-04-30 | 2965.16 | 未披露 |
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from December 31, 2019 to March 31, 2020
Sale of common stock and pre-funded warrants, net of underwriters' discount and costs
Exercise of stock options
|
2020-03-31 |
| 2020-02-27 | 2963.70 | 未披露 | 定期报告 | 2020-02-21 |
| 2020-01-30 | 2859.36 | 未披露 |
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1.Common Stock offered by us 4,752,420 shares
2.The number of shares of our common stock to be outstanding after this offering is based on the 23,841,155 shares of our common stock outstanding as of September 30, 2019
|
2020-01-30 |
| 2020-02-27 | 2386.51 | 未披露 |
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from December 31, 2018 to December 31, 2019
Exercise of stock options
Release of restricted stock units
Exercise of stock warrants
Proceeds from at-the-market offering, net of issuance costs
|
2019-12-31 |
| 2019-11-07 | 2384.12 | 未披露 |
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from June 30, 2019 to September 30, 2019
Exercise of stock options
Proceeds from at-the-market offering
|
2019-09-30 |
| 2019-08-01 | 2379.98 | 未披露 | 定期报告 | 2019-07-26 |
| 2019-08-01 | 2379.63 | 未披露 |
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from March 31, 2019 to June 30,2019
Exercise of stock options
|
2019-06-30 |
| 2019-05-02 | 2379.63 | 未披露 | 定期报告 | 2019-04-30 |
| 2019-05-02 | 2375.68 | 未披露 |
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from December 31, 2018 to March 31, 2019
Exercise of stock options
Release of restricted stock units
Exercise of stock warrants
|
2019-03-31 |
| 2019-02-28 | 2352.93 | 未披露 | 定期报告 | 2019-02-22 |
| 2019-02-28 | 2343.76 | 未披露 |
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from December 31, 2017 to December 31, 2018
Exercise of stock options
Release of restricted stock units
|
2018-12-31 |
| 2018-11-01 | 2342.94 | 未披露 | 定期报告 | 2018-10-29 |
| 2018-11-01 | 2342.83 | 未披露 | 定期报告 | 2018-09-30 |
| 2018-08-02 | 2341.50 | 未披露 | 定期报告 | 2018-07-30 |
| 2018-08-02 | 2341.46 | 未披露 | 定期报告 | 2018-06-30 |
| 2018-05-03 | 2339.58 | 未披露 | 定期报告 | 2018-05-01 |
| 2018-05-03 | 2339.31 | 未披露 | 定期报告 | 2018-04-17 |
| 2018-05-03 | 2338.96 | 未披露 | 定期报告 | 2018-03-31 |
| 2018-03-01 | 2323.33 | 未披露 | 定期报告 | 2018-02-26 |
| 2018-03-01 | 2322.67 | 未披露 | 定期报告 | 2018-01-31 |
| 2018-03-01 | 2314.04 | 未披露 |
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from December 31, 2016 to December 31, 2017
Exercise of stock options
|
2017-12-31 |
| 2017-11-09 | 2277.26 | 未披露 | 定期报告 | 2017-11-06 |
| 2017-11-09 | 2275.13 | 未披露 | 定期报告 | 2017-09-30 |
| 2017-08-08 | 2268.72 | 未披露 | 定期报告 | 2017-08-04 |
| 2017-08-08 | 2261.61 | 未披露 | 定期报告 | 2017-06-30 |
| 2017-05-02 | 2256.29 | 未披露 | 定期报告 | 2017-04-28 |
| 2017-04-26 | 2255.90 | 未披露 | 定期报告 | 2017-04-24 |
| 2017-05-02 | 2254.99 | 未披露 | 定期报告 | 2017-03-31 |
| 2017-03-06 | 2232.90 | 未披露 | 定期报告 | 2017-02-27 |
| 2017-04-26 | 2232.30 | 未披露 | 定期报告 | 2017-01-31 |
| 2017-03-06 | 2231.70 | 未披露 |
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From December 31, 2015 to December 31, 2016
Exercise of stock options
|
2016-12-31 |
| 2016-11-08 | 2227.43 | 未披露 | 定期报告 | 2016-11-03 |
| 2016-11-08 | 2223.93 | 未披露 | 定期报告 | 2016-09-30 |
| 2016-08-09 | 2222.80 | 未披露 | 定期报告 | 2016-08-03 |
| 2016-08-09 | 2222.41 | 未披露 | 定期报告 | 2016-06-30 |
| 2016-05-05 | 2221.67 | 未披露 | 定期报告 | 2016-04-29 |
| 2016-04-25 | 2221.16 | 未披露 | 定期报告 | 2016-04-14 |
| 2016-05-05 | 2220.92 | 未披露 | 定期报告 | 2016-03-31 |
| 2016-03-01 | 2220.43 | 未披露 | 定期报告 | 2016-02-23 |
| 2016-03-01 | 2216.52 | 未披露 |
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From December 31, 2014 to December 31, 2015
Proceeds from public offering, net of underwriting discounts and offering expenses
Exercise of stock options
|
2015-12-31 |
| 2015-11-05 | 2208.37 | 未披露 | 定期报告 | 2015-10-30 |
| 2015-11-05 | 2206.38 | 未披露 | 定期报告 | 2015-09-30 |
| 2015-08-05 | 2192.07 | 未披露 | 定期报告 | 2015-07-31 |
| 2015-08-05 | 2185.99 | 未披露 | 定期报告 | 2015-06-30 |
| 2015-05-11 | 2172.16 | 未披露 | 定期报告 | 2015-05-06 |
| 2015-04-20 | 2170.50 | 未披露 | 定期报告 | 2015-04-13 |
| 2015-05-11 | 2170.15 | 未披露 | 定期报告 | 2015-03-31 |
| 2015-03-02 | 1828.65 | 未披露 | 定期报告 | 2015-02-23 |
| 2015-03-02 | 1823.41 | 未披露 |
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From December 31,2013 to December 31,2014
Conversion of preferred stock into common stock
Proceeds from IPO, net of underwriting discounts and offering expenses
Exercise of stock options
All outstanding shares of our preferred stock into 9,919,821 shares of common stock that will become effective upon the closing of this offering
Gives effect to a 1-for-5.65 reverse split of our common stock effected on January 29, 2014
|
2014-12-31 |
| 2014-11-12 | 1818.63 | 未披露 | 定期报告 | 2014-09-30 |
| 2014-08-12 | 1801.38 | 未披露 | 定期报告 | 2014-06-30 |
| 2014-05-14 | 1789.96 | 未披露 | 定期报告 | 2014-03-31 |
| 2014-03-31 | 1789.96 | 未披露 | 定期报告 | 2014-03-28 |
| 2014-02-13 | 1721.81 | 未披露 |
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All outstanding shares of our preferred stock into 9,919,821 shares of common stock that will become effective upon the closing of this offering
Gives effect to a 1-for-5.65 reverse split of our common stock effected on January 29, 2014
|
2014-02-13 |
| 2014-02-03 | 129.52 | 5604.71 |
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The Company’s Board of Directors and stockholders approved a 1-for-5.65 reverse stock split of the Company’s common stock. The reverse stock split became effective on January 29, 2014.
|
2014-01-30 |
| 2014-03-31 | 129.83 | 5604.71 |
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From December 31,2012 to December 31,2013
Exercise of stock options
|
2013-12-31 |
| 2014-01-13 | 731.80 | 5604.71 |
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from December 31, 2012 to September 30, 2013
Exercise of stock option
|
2013-09-30 |
From June 30, 2022 to September 30, 2022
Exercise of warrants
From March 31, 2022 to June 30, 2022
Release of restricted stock units
Conversion of preferred stock
Exercise of warrants
Sale of common stock, net of underwriters' discount and costs
1.Common stock offered by 10,000,000 shares.
2.The number of shares of common stock to be outstanding after this offering is based on the 34,953,342 shares of common stock outstanding as of March 31, 2022.
From December 31, 2021 to March 31, 2022
Release of restricted stock units
From December 31, 2020 to December 31, 2021
Exercise of stock options
Release of restricted stock units
Proceeds from at-the-market offering, net of issuance costs
Sale of common and preferred stock, warrants and royalty interest (2021 Financing), net of issuance costs
1.Common stock to be offered 2,253,000 shares.
2.The above discussion is based on 32,173,778 shares of common stock outstanding as of June 30, 2021.
From June 30, 2021 to September 30, 2021
Release of restricted stock units
from December 31, 2020 to March 31, 2021
Exercise of stock options
Release of restricted stock units
Proceeds from at-the-market offering, net of issuance costs
From December 31, 2019 to December 31, 2020
Exercise of stock options
Release of restricted stock units
Sale of common stock and pre-funded warrants, net of underwriters' discount and costs
Proceeds from at-the-market offering, net of issuance costs
From June 30, 2020 to September 30, 2020
Exercise of stock options
Release of restricted stock units
From March 31, 2020 to June 30, 2020
Exercise of stock options
from December 31, 2019 to March 31, 2020
Sale of common stock and pre-funded warrants, net of underwriters' discount and costs
Exercise of stock options
1.Common Stock offered by us 4,752,420 shares
2.The number of shares of our common stock to be outstanding after this offering is based on the 23,841,155 shares of our common stock outstanding as of September 30, 2019
from December 31, 2018 to December 31, 2019
Exercise of stock options
Release of restricted stock units
Exercise of stock warrants
Proceeds from at-the-market offering, net of issuance costs
from June 30, 2019 to September 30, 2019
Exercise of stock options
Proceeds from at-the-market offering
from March 31, 2019 to June 30,2019
Exercise of stock options
from December 31, 2018 to March 31, 2019
Exercise of stock options
Release of restricted stock units
Exercise of stock warrants
from December 31, 2017 to December 31, 2018
Exercise of stock options
Release of restricted stock units
from December 31, 2016 to December 31, 2017
Exercise of stock options
From December 31, 2015 to December 31, 2016
Exercise of stock options
From December 31, 2014 to December 31, 2015
Proceeds from public offering, net of underwriting discounts and offering expenses
Exercise of stock options
From December 31,2013 to December 31,2014
Conversion of preferred stock into common stock
Proceeds from IPO, net of underwriting discounts and offering expenses
Exercise of stock options
All outstanding shares of our preferred stock into 9,919,821 shares of common stock that will become effective upon the closing of this offering
Gives effect to a 1-for-5.65 reverse split of our common stock effected on January 29, 2014
All outstanding shares of our preferred stock into 9,919,821 shares of common stock that will become effective upon the closing of this offering
Gives effect to a 1-for-5.65 reverse split of our common stock effected on January 29, 2014
The Company’s Board of Directors and stockholders approved a 1-for-5.65 reverse stock split of the Company’s common stock. The reverse stock split became effective on January 29, 2014.
From December 31,2012 to December 31,2013
Exercise of stock options
from December 31, 2012 to September 30, 2013
Exercise of stock option