MYOV

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From September 30, 2022 to December 31, 2022 Issuance of shares upon exercise of stock options and release of share awards

From June 30, 2022 to September 30, 2022 Issuance of shares upon exercise of stock options and release of share awards

From March 31, 2022 to June 30, 2022 Issuance of shares upon exercise of stock options and release of share awards

From March 31, 2021 to March 31, 2022 Issuance of shares upon exercise of stock options and release of share awards

From September 30, 2021 to December 31, 2021 Issuance of shares upon exercise of stock options and release of restricted stock units

From June 30, 2021 to September 30, 2021 Issuance of shares upon exercise of stock options and release of restricted stock units and performance share units

From March 31, 2021 to June 30, 2021 Issuance of shares upon exercise of stock options and vesting of restricted stock units

From March 31, 2019 to March 31, 2021 Vesting of share awards, net of shares withheld for taxes Issuance of shares upon exercise of stock options

from September 30, 2020 to December 31, 2020 Issuance of shares upon exercise of stock options and vesting of restricted stock units and performance share units

from June 30, 2020 to September 30, 2020 Issuance of shares upon exercise of stock options and vesting of restricted stock units and performance share units

from March 31, 2020 to June 30, 2020 Issuance of shares upon exercise of stock options and vesting of restricted stock units

from March 31, 2019 to March 31, 2020 Issuance of shares in connection with “at-the-market” equity offering, net of commissions of $79 Issuance of shares in connection with public equity offering, net of commissions and offering costs of $9,292 Issuance of shares upon exercise of stock options and vesting of PSUs and RSUs

from September 30, 2019 to December 31, 2019 Issuance of shares upon vesting of RSUs

from June 30, 2019 to September 30, 2019 Issuance of shares upon vesting of RSUs

from March 31, 2019 to June 14,2019 Issuance of shares in connection with “at-the-market” equity offering, net of commissions of $79 Issuance of shares in connection with public equity offering, net of commissions and offering costs of $9,229 Issuance of shares upon exercise of stock options and vesting of RSUs

from March 31, 2018 to March 31, 2019 Issuance of shares in connection with “at-the-market” equity offering, net of commissions and offering costs of $2,919 Issuance of shares in connection with Private Placement with RSL Issuance of shares in public equity offering, net of commissions and offering costs of $5,110 Shares issued to NovaQuest, net of issuance costs Issuance of shares upon exercise of stock options and vesting of RSUs

From September 30, 2018 to December 31, 2018 Shares issued to NovaQuest, net of issuance costs Issuance of shares upon exercise of stock options and vesting of RSUs

From June 30, 2018 to September 30, 2018 Issuance of common shares in secondary public equity offering, net of commissions and offering costs of $5.1 million Issuance of common shares upon exercise of stock options and vesting of RSUs

From March 31, 2018 to June 30, 2018 Issuance of common shares in connection with “at-the-market” equity offering, net of commissions and offering costs of $2.1 million Issuance of common shares in connection with Private Placement with RSL Issuance of common shares upon exercise of stock options

From March 31, 2017 to March 31, 2018 Shares issued to settle the Takeda warrant liability Share-based compensation expense Stock option exercises Shares issued to NovaQuest, net of underwriting discounts, commissions and offering costs of $0.1 million

From March 31, 2017 to December 31, 2017 Shares issued to settle the Takeda warrant liability Share-based compensation expense Stock option exercises Shares issued to NovaQuest, net of underwriting discounts and commissions and offering expenses of $0.1 million

From March 31, 2017 to September 30, 2017 Shares issued to settle the warrant liability to Takeda Share-based compensation expense Stock option exercises

From March 31, 2017 to July 14, 2017 Shares issued to settle the warrant liability to Takeda Share-based compensation expense

from March 31, 2016 to March 31, 2017 Sale of common shares in initial public offering ($15.00 per share), net of underwriting discounts and commissions and offering expenses of $17,536 Shares issued to Takeda under the Takeda license agreement Shares issued to settle the warrant liability to Takeda Share-based compensation expense

from March 31, 2016 to December 31, 2016 Sale of common shares in initial public offering ($15.00 per share), net of underwriting discounts and commissions and offering expenses of $17,536 Shares issued to Takeda under the Takeda license agreement Shares issued to settle the warrant liability to Takeda Share-based compensation expense

A 1-for-1.7727 reverse stock split effected on October 18, 2016; An aggregate of 160,273 common shares issued to Takeda in August and September 2016 upon the automatic exercise of a warrant we issued to Takeda at an exercise price of $0.000017727 per share, which was initiated by the grant of stock options for an aggregate of 1,175,311 common shares; The issuance of an additional 1,977,269 common shares to Takeda upon the closing of this offering pursuant to the automatic exercise of a warrant we issued to Takeda, based upon the sale and issuance of 14,500,000 common shares to investors in this offering at the initial public offering price of $15.00 per common share; No exercise by the underwriters of their option to purchase an additional 2,175,000 common shares and no issuance of an additional 296,593 common shares to Takeda as a result thereof, pursuant to the automatic exercise of a warrant we issued to Takeda;

From March 31, 2016 to September 30, 2016 Shares issued to Takeda under the Takeda license agreement Shares issued to settle the warrant liability to Takeda Share-based compensation expense