PETX

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from December 31, 2018 to March 31, 2019 Vesting of restricted stock awards Repurchase of common stock Issuance of common stock related to option exercises

from December 31, 2017 to December 31, 2018 At-the-Market issuance of common stock, net of $171 of issuance costs Vesting of restricted stock awards Repurchase of common stock Issuance of common stock related to option exercises

from December 31, 2016 to December 31, 2017 At-the-Market issuance of common stock, net of $73 of issuance costs Registered direct offering of common stock, net of $273 of issuance costs Vesting of restricted stock awards Repurchase of common stock Vesting of stock awards early exercised Issuance of common stock related to option exercises

From December 31, 2015 to December 31, 2016 At-the-Market issuance of common stock, net of $262 of issuance costs Vesting of restricted stock awards Vesting of stock awards early exercised Issuance of common stock related to option exercises

from December 31, 2014 to December 31, 2015 Vesting of restricted stock awards Repurchase of common stock Vesting of stock awards early exercised Issuance of common stock related to option exercises

from December 31, 2013 to December 31, 2014 Public offering of common stock, net of $10,627 of offering costs Vesting of restricted stock awards Repurchase of common stock Vesting of stock awards early exercised Issuance of common stock related to option exercises

from December 31, 2012 to December 31, 2013 Issuance of Series C convertible preferred stock, net of issuance cost of $19 Impact of initial public offering on stockholders’ deficit: Effect of a 1 for 1.662 reverse split on preferred stock Conversion of shares of preferred stock to common stock Dividends for preferred shares issued upon initial public offering Initial public offering of common stock, net of $5,394 of offering costs Issuance of common stock relating to Vet Therapeutics, Inc. acquisition Issuance of common stock related to private investment in public entity Vesting of restricted stock awards Vesting of stock awards early exercised Issuance of common stock related to stock option exercises

from December 31, 2012 to September 30, 2013 Impact of initial public offering on stockholders’ deficit: Effect of a 1 for 1.662 reverse split on preferred stock Conversion of shares of preferred stock to common stock Effect of a 1 for 1.662 reverse split on common stock Dividends for preferred shares issued upon initial public offering Initial public offering of common stock, net of $5,394 of offering costs Vesting of restricted stock Vesting of stock awards early exercised

In July 2013, the Company completed its initial public offering，Upon the closing of the initial public offering, all shares of the Company’s then-outstanding convertible preferred stock and accumulated dividends automatically converted into an aggregate of 13,351,902 shares of common stock.

a 1-for-1.662 reverse split of our common stock effected on May 22, 2013 the automatic conversion of all outstanding shares of our convertible preferred stock into 12,596,115 shares of our common stock immediately prior to the closing of the offering

from December 31, 2012 to May 23, 2013 Issuance of Series C convertible preferred stock, net of issuance cost of $19 Vesting of restricted stock Vesting of stock awards early exercised On May 22, 2013, the Company effected a 1-for-1.662 reverse stock split of its issued and outstanding shares of common stock and a proportional adjustment to the conversion ratio for each series of Convertible Preferred Stock.

from December 31, 2012 to March 31, 2013 Issuance of Series C convertible preferred stock, net of issuance cost of $19 Vesting of restricted stock Vesting of stock awards early exercised

from December 31, 2011 to December 31, 2012 Issuance of Series B convertible preferred stock, net of issuance cost of $13 Issuance of Series C convertible preferred stock, net of issuance cost of $55 Issuance of restricted stock awards to employees Issuance of common stock upon exercise of options