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股本结构

单位：万股
公告日期 2024-03-21 2024-03-14 2024-03-21 2023-11-09 2023-08-08 2023-05-11
证券总股本 6546.53 2035.53 2022.27 2022.27 1948.45 1685.97
普通股本 6546.53 2035.53 2022.27 2022.27 1948.45 1685.97
优先股 未披露 571.28 571.28 557.20 557.20 未披露
其他 未披露 未披露 未披露 未披露 未披露 未披露
变动日期 2024-03-15 2024-03-11 2023-12-31 2023-09-30 2023-06-30 2023-03-31
注释：中概股证券总股本=普通股股本/ 存托凭证比例

历史变动

公告日期 变动后普通股本（万股） 变动后优先股（万股） 变动原因 变动日期
2024-03-21 6546.53 未披露 定期报告 2024-03-15
2024-03-14 2035.53 571.28 定期报告 2024-03-11
2024-03-21 2022.27 571.28
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From December 31,2022 to December 31,2023 Issuance of common stock and preferred stock from private placement, net of offering costs Issuance of common stock under Employee Stock Purchase Plan Issuance of common stock through ATM
2023-12-31
2023-11-09 2022.27 557.20
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From June 30, 2023 to September 30, 2023 Issuance of common stock through ATM Issuance of common stock under Employee Stock Purchase Plan
2023-09-30
2023-08-08 1948.45 557.20
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From March 31, 2023 to June 30, 2023 Issuance of common stock and preferred stock from private placement, net of offering costs Issuance of common stock through ATM
2023-06-30
2023-04-28 1947.53 未披露 定期报告 2023-04-19
2023-05-11 1685.97 557.20
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From December 31, 2022 to March 31, 2023 Issuance of common stock under Employee Stock Purchase Plan
2023-03-31
2022-11-14 1684.03 557.20
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From June 30, 2022 to September 30, 2022 Issuance of common stock through ATM Issuance of common stock under Employee Stock Purchase Plan
2022-09-30
2022-08-11 1463.44 557.20
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From March 31, 2022 to June 30, 2022 Issuance of common stock upon vesting of restricted stock units
2022-06-30
2022-06-27 1459.81 未披露
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Pursuant to the Charter Amendment, effective at 5:00 p.m. Eastern Time on June 28, 2022 (the “Effective Time”), every ten shares of the Company’s issued and outstanding common stock will be automatically converted into one issued and outstanding share of common stock, without any change in par value per share.
2022-06-29
2022-05-13 14598.12 未披露
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From December 31, 2021 to March 31, 2022 Issuance of common stock under Employee Stock Purchase Plan
2022-03-31
2022-03-11 14597.12 557.20
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From December 31, 2020 to December 31, 2021 Issuance of common stock upon exercise of options Issuance of common stock upon exercise of warrants Issuance of common stock upon vesting of restricted stock units Issuance of common stock, preferred stock and warrants from private placement, net of offering costs Issuance of common stock under Employee Stock Purchase Plan Issuance of common stock through ATM Conversions of convertible preferred stock
2021-12-31
2021-12-02 14597.12 未披露 定期报告 2021-11-30
2021-11-12 8704.78 317.71
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From June 30, 2021 to September 30, 2021 Issuance of common stock under Employee Stock Purchase Plan
2021-09-30
2021-08-10 8704.03 317.71
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From March 31, 2021 to June 30, 2021 Conversions of convertible preferred stock Issuance of common stock upon vesting of restricted stock units Issuance of common stock upon exercise of options Issuance of common stock upon exercise of warrants Issuance of common stock through ATM
2021-06-30
2021-04-30 7492.37 未披露 定期报告 2021-04-16
2021-05-14 7468.91 185.38
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From December 31, 2020 To March 31, 2021 Issuance of common stock upon vesting of restricted stock units Issuance of common stock upon exercise of options Issuance of common stock upon exercise of warrants Issuance of common stock through ATM Issuance of common stock under Employee Stock Purchase Plan Conversions of convertible preferred stock
2021-03-31
2021-03-09 7250.48 未披露 定期报告 2021-02-28
2021-03-09 6743.27 193.19
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From December 31, 2019 to December 31, 2020 Issuance of common stock upon exercise of options Issuance of common stock upon exercise of warrants Issuance of common stock upon vesting of restricted stock units Issuance of common stock, preferred stock and warrants from private placement, net of offering costs Issuance of common stock under Employee Stock Purchase Plan Issuance of common stock through ATM Conversions of convertible preferred stock
2020-12-31
2020-12-31 6690.10 未披露 定期报告 2020-12-11
2020-11-05 3916.31 189.62
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From June 30, 2020 to September 30, 2020 Conversions of convertible preferred stock Issuance of common stock upon vesting of restricted stock units Issuance of common stock under Employee Stock Purchase Plan
2020-09-30
2020-08-13 3592.29 221.80
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From March 31, 2020 to June 30, 2020 Conversions of convertible preferred stock Issuance of common stock upon vesting of restricted stock units
2020-06-30
2020-05-14 2760.88 304.76
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From December 31, 2019 to March 31, 2020 Conversions of convertible preferred stock Issuance of common stock upon vesting of restricted stock units Issuance of common stock upon exercise of options Issuance of common stock under Employee Stock Purchase Plan
2020-03-31
2020-03-12 2104.01 未披露 定期报告 2020-03-06
2020-03-12 2101.87 370.43
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from December 31, 2018 to December 31, 2019 Issuance of common stock, preferred stock and warrants from private placement, net of offering costs Issuance of common stock upon exercise of options Issuance of common stock upon vesting of restricted stock units Issuance of common stock under Employee Stock Purchase Plan Issuance of common stock through ATM
2019-12-31
2019-11-12 2092.71 41.59
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from June 30, 2019 to September 30, 2019 Issuance of common stock upon exercise of options Issuance of common stock upon vesting of restricted stock units Issuance of common stock under Employee Stock Purchase Plan
2019-09-30
2019-08-08 2082.46 未披露 定期报告 2019-08-02
2019-08-08 2082.44 41.59
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from March 31, 2019 to June 30, 2019 Issuance of common stock, preferred stock and warrants from private placement, net of offering costs Issuance of common stock upon exercise of options Issuance of common stock upon vesting of restricted stock units
2019-06-30
2019-07-01 2076.63 未披露 定期报告 2019-06-28
2019-05-10 2054.85 未披露 定期报告 2019-05-07
2019-05-10 1081.79 未披露
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from December 31, 2018 to March 31, 2019 Issuance of common stock upon vesting of restricted stock units Issuance of common stock under Employee Stock Purchase Plan Issuance of common stock
2019-03-31
2019-03-18 1074.39 未披露 定期报告 2019-03-08
2019-03-18 881.80 未披露
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from December 31, 2017 to December 31, 2018 Issuance of common stock upon exercise of options Issuance of common stock upon vesting of restricted stock units Issuance of common stock under Employee Stock Purchase Plan
2018-12-31
2018-11-09 875.03 未披露 定期报告 2018-11-02
2018-10-04 880.00 未披露
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As a result of the reverse split, each 12 shares of the Company's issued and outstanding common stock were automatically combined and converted into one issued and outstanding share of common stock, par value $0.001 per share, and there are now approximately 8.8 million shares of common stock issued and outstanding. The common shares will trade under a new CUSIP number, 75915K 200, effective October 4, 2018, and remain listed on the Nasdaq Global Market under the symbol "RGLS".
2018-10-04
2018-09-06 10483.84 未披露 定期报告 2018-08-31
2018-08-09 10479.75 未披露 定期报告 2018-08-03
2018-08-09 10442.45 未披露 定期报告 2018-06-30
2018-05-10 10431.96 未披露 定期报告 2018-03-31
2018-03-08 10395.91 未披露 定期报告 2018-02-23
2018-03-08 10395.51 未披露
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from December 31, 2016 to September 30, 2017 Issuance of common stock upon exercise of options Issuance of common stock under Employee Stock Purchase Plan Issuance of common stock, net of $292 of offering costs
2017-09-30
2017-08-02 10378.57 未披露
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In July 2017,company completed an underwritten public offering of 50,600,000 shares of common stock at an offering price of $0.91 per share.
2017-07-28
2017-05-05 5318.23 未披露 定期报告 2017-03-31
2017-03-03 5293.24 未披露 定期报告 2017-02-24
2017-03-03 5292.48 未披露
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from December 31, 2015 to December 31, 2016 Issuance of common stock upon exercise of options Issuance of common stock under Employee Stock Purchase Plan
2016-12-31
2016-11-02 5292.33 未披露 定期报告 2016-09-30
2016-08-03 5282.03 未披露 定期报告 2016-07-29
2016-08-03 5278.78 未披露 定期报告 2016-06-30
2016-05-03 5278.10 未披露 定期报告 2016-04-27
2016-04-22 5278.10 未披露 定期报告 2016-04-08
2016-05-03 5266.93 未披露 定期报告 2016-03-31
2016-02-23 5270.48 未披露 定期报告 2016-02-19
2016-02-23 5266.93 未披露
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from December 31, 2014 to December 31, 2015 Issuance of common stock upon exercise of options Issuance of common stock under Employee Stock Purchase Plan Conversion of convertible note payable into common stock
2015-12-31
2015-11-06 5234.27 未披露 定期报告 2015-09-30
2015-08-05 5191.95 未披露 定期报告 2015-07-24
2015-08-04 5153.34 未披露 定期报告 2015-06-30
2015-05-08 5101.74 未披露 定期报告 2015-04-24
2015-04-30 5095.72 未披露 定期报告 2015-04-20
2015-04-08 5078.16 未披露 定期报告 2015-04-07
2015-05-07 5076.25 未披露 定期报告 2015-03-31
2015-04-30 5053.11 未披露 定期报告 2015-02-25
2015-02-19 5051.67 未披露 定期报告 2015-02-06
2015-02-19 4894.45 未披露
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from December 31, 2013 to December 31, 2014 Issuance of common stock upon exercise of options Issuance of common stock under Employee Stock Purchase Plan Issuance of common stock, net of $347 of offering costs Issuance of common stock in private placement
2014-12-31
2014-11-06 4860.38 未披露 定期报告 2014-11-03
2014-11-05 4343.96 未披露 定期报告 2014-09-30
2014-08-07 4339.23 未披露 定期报告 2014-07-25
2014-08-07 4338.39 未披露 定期报告 2014-06-30
2014-05-09 4335.68 未披露 定期报告 2014-04-25
2014-05-09 4334.60 未披露 定期报告 2014-03-31
2014-04-11 4333.56 未披露 定期报告 2014-03-28
2014-04-14 4322.06 未披露 定期报告 2014-02-28
2014-02-28 4316.80 未披露 定期报告 2014-02-07
2014-02-28 4178.73 未披露
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from December 31, 2012 to December 31, 2013 Issuance of common stock upon exercise of options Issuance of common stock under Employee Stock Purchase Plan Issuance of common stock, net of $434 of offering costs
2013-12-31
2013-11-14 4177.73 未披露 定期报告 2013-11-08
2013-11-14 4177.44 未披露 定期报告 2013-09-30
2013-08-14 3615.57 未披露 定期报告 2013-08-12
2013-08-14 3608.16 未披露 定期报告 2013-06-30
2013-05-15 3600.73 未披露 定期报告 2013-05-10
2013-04-30 3598.24 未披露 定期报告 2013-04-11
2013-05-15 3596.54 未披露 定期报告 2013-03-31
2013-02-19 3588.31 未披露 定期报告 2013-02-14
2013-02-19 3583.18 未披露
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from December 31, 2011 to December 31, 2012 Effect of 2-for-1 split on shares of preferred stock Conversion of shares of preferred stock to common stock Initial public offering of common stock, net of $5,886 of offering costs Issuance of common stock in private placement concurrently with initial public offering, net Conversion of notes payable to common stock
2012-12-31
2012-11-19 3582.90 未披露
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On October 10, 2012, we completed our IPO,Upon the closing of the IPO, all shares of our convertible preferred stock automatically converted into 13,699,999 shares of our common stock.
2012-11-16
2012-10-05 3413.04 未披露
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reflects the conversion of all our outstanding convertible preferred stock into an aggregate of 13,699,999 shares of common stock in connection with the closing of this offering; reflects a one-for-two reverse stock split of our common stock effected in September 2012.
2012-10-04
2012-11-19 42.51 2740.00 定期报告 2012-09-30
2012-08-17 24.34 2740.00
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from December 31, 2011 to June 30, 2012 Issuance of common stock upon exercise of options (unaudited)
2012-06-30
From December 31,2022 to December 31,2023 Issuance of common stock and preferred stock from private placement, net of offering costs Issuance of common stock under Employee Stock Purchase Plan Issuance of common stock through ATM
From June 30, 2023 to September 30, 2023 Issuance of common stock through ATM Issuance of common stock under Employee Stock Purchase Plan
From March 31, 2023 to June 30, 2023 Issuance of common stock and preferred stock from private placement, net of offering costs Issuance of common stock through ATM
From December 31, 2022 to March 31, 2023 Issuance of common stock under Employee Stock Purchase Plan
From June 30, 2022 to September 30, 2022 Issuance of common stock through ATM Issuance of common stock under Employee Stock Purchase Plan
From March 31, 2022 to June 30, 2022 Issuance of common stock upon vesting of restricted stock units
Pursuant to the Charter Amendment, effective at 5:00 p.m. Eastern Time on June 28, 2022 (the “Effective Time”), every ten shares of the Company’s issued and outstanding common stock will be automatically converted into one issued and outstanding share of common stock, without any change in par value per share.
From December 31, 2021 to March 31, 2022 Issuance of common stock under Employee Stock Purchase Plan
From December 31, 2020 to December 31, 2021 Issuance of common stock upon exercise of options Issuance of common stock upon exercise of warrants Issuance of common stock upon vesting of restricted stock units Issuance of common stock, preferred stock and warrants from private placement, net of offering costs Issuance of common stock under Employee Stock Purchase Plan Issuance of common stock through ATM Conversions of convertible preferred stock
From June 30, 2021 to September 30, 2021 Issuance of common stock under Employee Stock Purchase Plan
From March 31, 2021 to June 30, 2021 Conversions of convertible preferred stock Issuance of common stock upon vesting of restricted stock units Issuance of common stock upon exercise of options Issuance of common stock upon exercise of warrants Issuance of common stock through ATM
From December 31, 2020 To March 31, 2021 Issuance of common stock upon vesting of restricted stock units Issuance of common stock upon exercise of options Issuance of common stock upon exercise of warrants Issuance of common stock through ATM Issuance of common stock under Employee Stock Purchase Plan Conversions of convertible preferred stock
From December 31, 2019 to December 31, 2020 Issuance of common stock upon exercise of options Issuance of common stock upon exercise of warrants Issuance of common stock upon vesting of restricted stock units Issuance of common stock, preferred stock and warrants from private placement, net of offering costs Issuance of common stock under Employee Stock Purchase Plan Issuance of common stock through ATM Conversions of convertible preferred stock
From June 30, 2020 to September 30, 2020 Conversions of convertible preferred stock Issuance of common stock upon vesting of restricted stock units Issuance of common stock under Employee Stock Purchase Plan
From March 31, 2020 to June 30, 2020 Conversions of convertible preferred stock Issuance of common stock upon vesting of restricted stock units
From December 31, 2019 to March 31, 2020 Conversions of convertible preferred stock Issuance of common stock upon vesting of restricted stock units Issuance of common stock upon exercise of options Issuance of common stock under Employee Stock Purchase Plan
from December 31, 2018 to December 31, 2019 Issuance of common stock, preferred stock and warrants from private placement, net of offering costs Issuance of common stock upon exercise of options Issuance of common stock upon vesting of restricted stock units Issuance of common stock under Employee Stock Purchase Plan Issuance of common stock through ATM
from June 30, 2019 to September 30, 2019 Issuance of common stock upon exercise of options Issuance of common stock upon vesting of restricted stock units Issuance of common stock under Employee Stock Purchase Plan
from March 31, 2019 to June 30, 2019 Issuance of common stock, preferred stock and warrants from private placement, net of offering costs Issuance of common stock upon exercise of options Issuance of common stock upon vesting of restricted stock units
from December 31, 2018 to March 31, 2019 Issuance of common stock upon vesting of restricted stock units Issuance of common stock under Employee Stock Purchase Plan Issuance of common stock
from December 31, 2017 to December 31, 2018 Issuance of common stock upon exercise of options Issuance of common stock upon vesting of restricted stock units Issuance of common stock under Employee Stock Purchase Plan
As a result of the reverse split, each 12 shares of the Company's issued and outstanding common stock were automatically combined and converted into one issued and outstanding share of common stock, par value $0.001 per share, and there are now approximately 8.8 million shares of common stock issued and outstanding. The common shares will trade under a new CUSIP number, 75915K 200, effective October 4, 2018, and remain listed on the Nasdaq Global Market under the symbol "RGLS".
from December 31, 2016 to September 30, 2017 Issuance of common stock upon exercise of options Issuance of common stock under Employee Stock Purchase Plan Issuance of common stock, net of $292 of offering costs
In July 2017,company completed an underwritten public offering of 50,600,000 shares of common stock at an offering price of $0.91 per share.
from December 31, 2015 to December 31, 2016 Issuance of common stock upon exercise of options Issuance of common stock under Employee Stock Purchase Plan
from December 31, 2014 to December 31, 2015 Issuance of common stock upon exercise of options Issuance of common stock under Employee Stock Purchase Plan Conversion of convertible note payable into common stock
from December 31, 2013 to December 31, 2014 Issuance of common stock upon exercise of options Issuance of common stock under Employee Stock Purchase Plan Issuance of common stock, net of $347 of offering costs Issuance of common stock in private placement
from December 31, 2012 to December 31, 2013 Issuance of common stock upon exercise of options Issuance of common stock under Employee Stock Purchase Plan Issuance of common stock, net of $434 of offering costs
from December 31, 2011 to December 31, 2012 Effect of 2-for-1 split on shares of preferred stock Conversion of shares of preferred stock to common stock Initial public offering of common stock, net of $5,886 of offering costs Issuance of common stock in private placement concurrently with initial public offering, net Conversion of notes payable to common stock
On October 10, 2012, we completed our IPO,Upon the closing of the IPO, all shares of our convertible preferred stock automatically converted into 13,699,999 shares of our common stock.
reflects the conversion of all our outstanding convertible preferred stock into an aggregate of 13,699,999 shares of common stock in connection with the closing of this offering; reflects a one-for-two reverse stock split of our common stock effected in September 2012.
from December 31, 2011 to June 30, 2012 Issuance of common stock upon exercise of options (unaudited)