股本结构
单位：万股
| 公告日期 | 2026-08-04 | 2026-08-04 | 2026-05-29 | 2026-05-05 | 2026-04-29 | 2026-05-05 |
|---|---|---|---|---|---|---|
| 证券总股本 | 6885.21 | 6881.69 | 6859.36 | 6853.26 | 6853.01 | 6844.51 |
| 普通股本 | 6885.21 | 6881.69 | 6859.36 | 6853.26 | 6853.01 | 6844.51 |
| 优先股 | 未披露 | 11.50 | 11.50 | 未披露 | 11.50 | 11.50 |
| 其他 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 |
| 变动日期 | 2026-08-01 | 2026-06-30 | 2026-05-22 | 2026-05-01 | 2026-04-27 | 2026-03-31 |
注释：中概股证券总股本=普通股股本/
存托凭证比例
历史变动
| 公告日期 | 变动后普通股本（万股） | 变动后优先股（万股） | 变动原因 | 变动日期 |
|---|---|---|---|---|
| 2026-08-04 | 6885.21 | 未披露 | 定期报告 | 2026-08-01 |
| 2026-08-04 | 6881.69 | 11.50 |
更多>>
From March 31, 2026 to June 30, 2026
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units
Tax withholding on vesting of restricted stock
|
2026-06-30 |
| 2026-05-29 | 6859.36 | 11.50 | 定期报告 | 2026-05-22 |
| 2026-05-05 | 6853.26 | 未披露 | 定期报告 | 2026-05-01 |
| 2026-04-29 | 6853.01 | 11.50 | 定期报告 | 2026-04-27 |
| 2026-05-05 | 6844.51 | 11.50 |
更多>>
From December 31, 2025 to March 31, 2026
Conversion of Series A preferred stock redeemable to common stock
Issuance of common stock in connection with ESPP
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units
Tax withholding on vesting of restricted stock
Conversion of Series A preferred stock redeemable to common stock
|
2026-03-31 |
| 2026-02-26 | 6828.50 | 未披露 | 定期报告 | 2026-02-24 |
| 2026-02-26 | 6720.53 | 13.25 |
更多>>
From December 31, 2024 to December 31, 2025
Issuance of common stock in connection with ESPP
Issuance of common stock upon completion of public offering, net of offering costs of $126 million
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units
Conversion of Series A preferred stock redeemable to common stock
Issuance of common stock upon completion of ATM equity offering, net of $07 million of offering costs
|
2025-12-31 |
| 2025-11-04 | 6673.61 | 未披露 | 定期报告 | 2025-10-31 |
| 2025-11-04 | 6668.41 | 15.00 |
更多>>
From June 30, 2025 to September 30, 2025
Issuance of common stock in connection with ESPP
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units
Issuance of common stock upon completion of public offering, net of $12.6 million of offering costs
|
2025-09-30 |
| 2025-08-05 | 6642.01 | 未披露 | 定期报告 | 2025-08-01 |
| 2025-07-10 | 6568.03 | 未披露 |
更多>>
Common stock offered 2,058,824 shares by the company
|
2025-07-11 |
| 2025-08-05 | 6391.32 | 15.00 |
更多>>
From March 31, 2025 to June 30, 2025
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units
|
2025-06-30 |
| 2025-05-07 | 6362.15 | 未披露 | 定期报告 | 2025-04-30 |
| 2025-04-29 | 6359.79 | 15.00 | 定期报告 | 2025-04-28 |
| 2025-05-07 | 6349.49 | 15.00 |
更多>>
From December 31, 2024 to March 31, 2025
Issuance of common stock in connection with ESPP
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units
Issuance of common stock upon completion of ATM equity offering, net of $739 offering costs
|
2025-03-31 |
| 2025-02-28 | 6322.37 | 未披露 | 定期报告 | 2025-02-24 |
| 2025-02-28 | 6239.07 | 15.00 |
更多>>
From December 31, 2023 to December 31, 2024
Issuance of common stock in connection with ESPP
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units
Issuance of common stock as consideration for LGC license
Issuance of common stock upon completion of ATM equity offering, net of $1,125 offering costs
|
2024-12-31 |
| 2024-11-06 | 6145.71 | 未披露 | 定期报告 | 2024-11-03 |
| 2024-11-06 | 6143.63 | 15.00 |
更多>>
From June 30, 2024 to September 30, 2024
Issuance of common stock in connection with ESPP
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units
|
2024-09-30 |
| 2024-08-14 | 6113.38 | 未披露 | 定期报告 | 2024-08-01 |
| 2024-08-07 | 6113.06 | 15.00 | 定期报告 | 2024-07-24 |
| 2024-08-06 | 6109.59 | 15.00 |
更多>>
From March 31, 2024 to June 30, 2024
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units
|
2024-06-30 |
| 2024-04-26 | 6097.29 | 未披露 | 定期报告 | 2024-04-22 |
| 2024-05-07 | 6096.45 | 未披露 |
更多>>
From December 31, 2023 to March 31, 2024
Issuance of common stock in connection with ESPP
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units
Issuance of common stock as consideration for LGC license
|
2024-03-31 |
| 2024-02-29 | 6014.05 | 未披露 | 定期报告 | 2024-02-23 |
| 2024-02-29 | 5942.66 | 未披露 |
更多>>
From December 31, 2022 to December 31, 2023
Issuance of common stock in connection with ESPP
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units
Issuance of common stock upon completion of ATM equity offering, net of offering costs
|
2023-12-31 |
| 2023-11-08 | 5909.65 | 未披露 | 定期报告 | 2023-11-01 |
| 2023-11-08 | 5908.94 | 未披露 |
更多>>
From June 30, 2023 to September 30, 2023
Issuance of common stock in connection with ESPP
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units
Issuance of common stock upon completion of ATM equity offering, net of offering costs
|
2023-09-30 |
| 2023-08-01 | 5690.15 | 未披露 | 定期报告 | 2023-07-26 |
| 2023-08-01 | 5689.61 | 未披露 | 定期报告 | 2023-06-30 |
| 2023-04-27 | 5685.49 | 未披露 | 定期报告 | 2023-04-24 |
| 2023-05-02 | 5685.24 | 未披露 |
更多>>
From December 31, 2022 to March 31, 2023
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units
Issuance of common stock in connection with ESPP
|
2023-03-31 |
| 2023-03-01 | 5674.76 | 未披露 | 定期报告 | 2023-02-22 |
| 2023-03-01 | 5661.24 | 未披露 |
更多>>
From December 31, 2021 to December 31, 2022
Issuance of common stock upon completion of public offering, net of offering costs
Issuance of common stock in connection with ESPP
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units
|
2022-12-31 |
| 2022-11-08 | 5634.83 | 未披露 | 定期报告 | 2022-11-02 |
| 2022-11-08 | 5575.63 | 未披露 |
更多>>
From June 30, 2022 to September 30, 2022
Issuance of common stock in connection with ESPP
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units
Issuance of common stock upon completion of public offering, net of offering costs
|
2022-09-30 |
| 2022-09-15 | 5572.00 | 未披露 | 定期报告 | 2022-09-19 |
| 2022-09-14 | 5092.00 | 未披露 | 定期报告 | 2022-08-31 |
| 2022-08-03 | 5072.06 | 未披露 | 定期报告 | 2022-07-28 |
| 2022-08-03 | 5045.42 | 未披露 |
更多>>
From March 31, 2022 to June 30, 2022
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units
|
2022-06-30 |
| 2022-05-03 | 5039.37 | 未披露 |
更多>>
From December 31, 2021 to March 31, 2022
Issuance of common stock in connection with ESPP
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units
|
2022-03-31 |
| 2022-03-01 | 5032.97 | 未披露 | 定期报告 | 2022-02-22 |
| 2022-03-01 | 5028.36 | 未披露 |
更多>>
From December 31, 2020 to December 31, 2021
Issuance of common stock in connection with ESPP
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units
Issuance of common stock upon completion of public offering, net of offering costs
|
2021-12-31 |
| 2021-11-02 | 5026.83 | 未披露 |
更多>>
From June 30, 2021 to September 30, 2021
Issuance of common stock in connection with ESPP
Issuance of common stock in connection with exercise of stock options
|
2021-09-30 |
| 2021-08-03 | 5022.75 | 未披露 | 定期报告 | 2021-07-26 |
| 2021-08-03 | 5022.67 | 未披露 |
更多>>
From March 31, 2021 to June 30, 2021
Issuance of common stock in connection with exercise of stock options
|
2021-06-30 |
| 2021-05-03 | 5020.68 | 未披露 | 定期报告 | 2021-04-23 |
| 2021-05-03 | 5020.18 | 未披露 |
更多>>
from December 31, 2020 to March 31, 2021
Issuance of common stock in connection with ESPP
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units
Issuance of common stock upon completion of public offering, net of offering costs
|
2021-03-31 |
| 2021-03-01 | 5018.12 | 未披露 | 定期报告 | 2021-02-19 |
| 2021-02-09 | 4923.59 | 未披露 |
更多>>
1.Common stock offered by the company 5,000,000 shares.
2.The number of shares of common stock to be outstanding after this offering is based on 44,235,903 shares outstanding as of December 31, 2020.
|
2021-02-09 |
| 2021-03-01 | 4423.59 | 未披露 |
更多>>
From December 31, 2019 to December 31, 2020
Issuance of common stock in connection with ESPP
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units
|
2020-12-31 |
| 2020-11-02 | 4420.47 | 未披露 |
更多>>
From June 30, 2020 to September 30, 2020
Issuance of common stock in connection with ESPP
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units
|
2020-09-30 |
| 2020-08-03 | 4411.86 | 未披露 | 定期报告 | 2020-07-24 |
| 2020-08-03 | 4411.56 | 未披露 |
更多>>
From March 31, 2020 to June 30, 2020
Issuance of common stock in connection with exercise of stock options
|
2020-06-30 |
| 2020-04-29 | 4409.18 | 未披露 | 定期报告 | 2020-04-20 |
| 2020-05-04 | 4408.84 | 未披露 |
更多>>
From December 31, 2019 to March 31, 2020
Issuance of common stock in connection with ESPP
Issuance of common stock in connection with exercise of stock options
|
2020-03-31 |
| 2020-03-02 | 4405.89 | 未披露 | 定期报告 | 2020-02-28 |
| 2020-03-02 | 4399.68 | 未披露 |
更多>>
From December 31, 2018 to December 31, 2019
Issuance of common stock in connection with ESPP
Issuance of common stock in connection with exercise of stock options
Issuance of common stock upon completion of public offering, net of offering costs
|
2019-12-31 |
| 2019-11-01 | 4392.64 | 未披露 | 定期报告 | 2019-10-31 |
| 2019-10-18 | 4382.19 | 未披露 | 定期报告 | 2019-10-18 |
| 2019-11-01 | 3457.86 | 未披露 |
更多>>
from June 30, 2019 to September 30, 2019
Issuance of common stock in connection with ESPP
Issuance of common stock in connection with exercise of stock options
|
2019-09-30 |
| 2019-07-29 | 3451.50 | 未披露 | 定期报告 | 2019-07-25 |
| 2019-07-29 | 3449.75 | 未披露 |
更多>>
from March 31, 2019 to June 30,2019
Issuance of common stock in connection with exercise of stock options
|
2019-06-30 |
| 2019-04-30 | 3443.22 | 未披露 | 定期报告 | 2019-04-22 |
| 2019-05-03 | 3443.06 | 未披露 |
更多>>
From December 31, 2018 to March 31, 2019
Issuance of common stock in connection with ESPP
Issuance of common stock in connection with exercise of stock options
|
2019-03-31 |
| 2019-03-08 | 3442.58 | 未披露 | 定期报告 | 2019-03-01 |
| 2019-03-08 | 3441.07 | 未披露 |
更多>>
From December 31, 2017 to December 31, 2018
Shares issued for license agreement
Issuance of common stock upon completion of public offering, net of offering costs
Issuance of common stock in connection with exercise of stock options
|
2018-12-31 |
| 2018-11-09 | 3441.07 | 未披露 | 定期报告 | 2018-11-08 |
| 2018-11-09 | 3438.25 | 未披露 | 定期报告 | 2018-09-30 |
| 2018-08-08 | 3417.51 | 未披露 | 定期报告 | 2018-08-03 |
| 2018-08-08 | 3417.31 | 未披露 | 定期报告 | 2018-06-30 |
| 2018-05-14 | 2753.02 | 未披露 | 定期报告 | 2018-05-11 |
| 2018-04-30 | 2751.77 | 未披露 | 定期报告 | 2018-04-16 |
| 2018-03-12 | 2728.41 | 未披露 |
更多>>
from December 31, 2016 to December 31, 2017
Issuance of Series A Convertible Preferred Stock
Conversion of Series A Convertible Preferred Stock and Series A-1 Junior Preferred Stock into common stock on a 9.17 to 1 basis
Issuance of common stock in connection with exercise of stock options
Exchange of common stock held by LLC entity for Series A-1 Junior Preferred Stock
Issuance of common stock upon completion of initial public offering, net of offering costs
|
2017-12-31 |
| 2017-11-14 | 2728.41 | 未披露 | 定期报告 | 2017-11-10 |
| 2017-10-05 | 2607.40 | 未披露 |
更多>>
1.Common stock offered by us 7,050,000 shares
2.The number of shares of our common stock to be outstanding after this offering is based on 19,023,984 shares of our common stock outstanding as of June 30, 2017
3.the 1-for-9.17 reverse stock split of our common stock, effective September 29, 2017
|
2017-10-05 |
| 2017-11-14 | 177.03 | 15961.62 |
更多>>
From December 31, 2016 to September 30, 2017
Issuance of Series A Convertible Preferred Stock
Issuance of common stock in connection with exercise of stock options
Exchange of common stock held by LLC entity for Series A-1 Junior Preferred Stock
|
2017-09-30 |
| 2017-09-25 | 1902.40 | 未披露 |
更多>>
from December 31, 2016 to June 30, 2017
Issuance of Series A Convertible Preferred Stock
|
2017-06-30 |
| 2014-08-27 | 1093.86 | 14600.00 |
更多>>
from December 31, 2013 to June 30, 2014
Vesting of restricted common units (unaudited)
|
2014-06-30 |
From March 31, 2026 to June 30, 2026
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units
Tax withholding on vesting of restricted stock
From December 31, 2025 to March 31, 2026
Conversion of Series A preferred stock redeemable to common stock
Issuance of common stock in connection with ESPP
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units
Tax withholding on vesting of restricted stock
Conversion of Series A preferred stock redeemable to common stock
From December 31, 2024 to December 31, 2025
Issuance of common stock in connection with ESPP
Issuance of common stock upon completion of public offering, net of offering costs of $126 million
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units
Conversion of Series A preferred stock redeemable to common stock
Issuance of common stock upon completion of ATM equity offering, net of $07 million of offering costs
From June 30, 2025 to September 30, 2025
Issuance of common stock in connection with ESPP
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units
Issuance of common stock upon completion of public offering, net of $12.6 million of offering costs
Common stock offered 2,058,824 shares by the company
From March 31, 2025 to June 30, 2025
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units
From December 31, 2024 to March 31, 2025
Issuance of common stock in connection with ESPP
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units
Issuance of common stock upon completion of ATM equity offering, net of $739 offering costs
From December 31, 2023 to December 31, 2024
Issuance of common stock in connection with ESPP
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units
Issuance of common stock as consideration for LGC license
Issuance of common stock upon completion of ATM equity offering, net of $1,125 offering costs
From June 30, 2024 to September 30, 2024
Issuance of common stock in connection with ESPP
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units
From March 31, 2024 to June 30, 2024
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units
From December 31, 2023 to March 31, 2024
Issuance of common stock in connection with ESPP
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units
Issuance of common stock as consideration for LGC license
From December 31, 2022 to December 31, 2023
Issuance of common stock in connection with ESPP
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units
Issuance of common stock upon completion of ATM equity offering, net of offering costs
From June 30, 2023 to September 30, 2023
Issuance of common stock in connection with ESPP
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units
Issuance of common stock upon completion of ATM equity offering, net of offering costs
From December 31, 2022 to March 31, 2023
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units
Issuance of common stock in connection with ESPP
From December 31, 2021 to December 31, 2022
Issuance of common stock upon completion of public offering, net of offering costs
Issuance of common stock in connection with ESPP
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units
From June 30, 2022 to September 30, 2022
Issuance of common stock in connection with ESPP
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units
Issuance of common stock upon completion of public offering, net of offering costs
From March 31, 2022 to June 30, 2022
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units
From December 31, 2021 to March 31, 2022
Issuance of common stock in connection with ESPP
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units
From December 31, 2020 to December 31, 2021
Issuance of common stock in connection with ESPP
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units
Issuance of common stock upon completion of public offering, net of offering costs
From June 30, 2021 to September 30, 2021
Issuance of common stock in connection with ESPP
Issuance of common stock in connection with exercise of stock options
From March 31, 2021 to June 30, 2021
Issuance of common stock in connection with exercise of stock options
from December 31, 2020 to March 31, 2021
Issuance of common stock in connection with ESPP
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units
Issuance of common stock upon completion of public offering, net of offering costs
1.Common stock offered by the company 5,000,000 shares.
2.The number of shares of common stock to be outstanding after this offering is based on 44,235,903 shares outstanding as of December 31, 2020.
From December 31, 2019 to December 31, 2020
Issuance of common stock in connection with ESPP
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units
From June 30, 2020 to September 30, 2020
Issuance of common stock in connection with ESPP
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units
From March 31, 2020 to June 30, 2020
Issuance of common stock in connection with exercise of stock options
From December 31, 2019 to March 31, 2020
Issuance of common stock in connection with ESPP
Issuance of common stock in connection with exercise of stock options
From December 31, 2018 to December 31, 2019
Issuance of common stock in connection with ESPP
Issuance of common stock in connection with exercise of stock options
Issuance of common stock upon completion of public offering, net of offering costs
from June 30, 2019 to September 30, 2019
Issuance of common stock in connection with ESPP
Issuance of common stock in connection with exercise of stock options
from March 31, 2019 to June 30,2019
Issuance of common stock in connection with exercise of stock options
From December 31, 2018 to March 31, 2019
Issuance of common stock in connection with ESPP
Issuance of common stock in connection with exercise of stock options
From December 31, 2017 to December 31, 2018
Shares issued for license agreement
Issuance of common stock upon completion of public offering, net of offering costs
Issuance of common stock in connection with exercise of stock options
from December 31, 2016 to December 31, 2017
Issuance of Series A Convertible Preferred Stock
Conversion of Series A Convertible Preferred Stock and Series A-1 Junior Preferred Stock into common stock on a 9.17 to 1 basis
Issuance of common stock in connection with exercise of stock options
Exchange of common stock held by LLC entity for Series A-1 Junior Preferred Stock
Issuance of common stock upon completion of initial public offering, net of offering costs
1.Common stock offered by us 7,050,000 shares
2.The number of shares of our common stock to be outstanding after this offering is based on 19,023,984 shares of our common stock outstanding as of June 30, 2017
3.the 1-for-9.17 reverse stock split of our common stock, effective September 29, 2017
From December 31, 2016 to September 30, 2017
Issuance of Series A Convertible Preferred Stock
Issuance of common stock in connection with exercise of stock options
Exchange of common stock held by LLC entity for Series A-1 Junior Preferred Stock
from December 31, 2016 to June 30, 2017
Issuance of Series A Convertible Preferred Stock
from December 31, 2013 to June 30, 2014
Vesting of restricted common units (unaudited)