股本结构
单位：万股
| 公告日期 | 2026-08-04 | 2026-08-04 | 2026-04-29 | 2026-06-29 | 2026-03-04 | 2026-03-04 |
|---|---|---|---|---|---|---|
| 证券总股本 | 7912.60 | 7890.80 | 7964.43 | 7962.42 | 8008.05 | 7971.40 |
| 普通股本 | 7912.60 | 7890.80 | 7964.43 | 7962.42 | 8008.05 | 7971.40 |
| 优先股 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 |
| 其他 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 |
| 变动日期 | 2026-07-30 | 2026-06-30 | 2026-04-27 | 2026-03-31 | 2026-03-03 | 2025-12-31 |
注释：中概股证券总股本=普通股股本/
存托凭证比例
历史变动
| 公告日期 | 变动后普通股本（万股） | 变动后优先股（万股） | 变动原因 | 变动日期 |
|---|---|---|---|---|
| 2026-08-04 | 7912.60 | 未披露 | 定期报告 | 2026-07-30 |
| 2026-08-04 | 7890.80 | 未披露 |
更多>>
From April 1, 2026 to June 30, 2026
Common stock repurchase
Exercise of stock options
Issuance of common stock from ESPP
Issuance of restricted stock
|
2026-06-30 |
| 2026-04-29 | 7964.43 | 未披露 | 定期报告 | 2026-04-27 |
| 2026-06-29 | 7962.42 | 未披露 | 定期报告 | 2026-03-31 |
| 2026-03-04 | 8008.05 | 未披露 | 定期报告 | 2026-03-03 |
| 2026-03-04 | 7971.40 | 未披露 |
更多>>
From December 31, 2024 to December 31, 2025
Issuance of restricted stock
Exercise of stock options
Common stock repurchase
|
2025-12-31 |
| 2025-11-04 | 7980.61 | 未披露 | 定期报告 | 2025-11-03 |
| 2025-11-04 | 7963.90 | 未披露 |
更多>>
From July 1, 2025 to September 30, 2025
Issuance of common stock resulting from the exercise of stock options
|
2025-09-30 |
| 2025-08-06 | 7975.30 | 未披露 | 定期报告 | 2025-08-04 |
| 2025-08-06 | 7958.60 | 未披露 |
更多>>
From April 1, 2025 to June 30, 2025
Issuance of common stock resulting from the exercise of stock options
Issuance of restricted stock
|
2025-06-30 |
| 2025-05-07 | 7876.97 | 未披露 | 定期报告 | 2025-05-05 |
| 2025-04-29 | 7868.43 | 未披露 | 定期报告 | 2025-04-25 |
| 2025-05-07 | 7843.32 | 未披露 |
更多>>
From January 1, 2025 to March 31, 2025
Issuance of restricted stock
Exercise of stock options
|
2025-03-31 |
| 2025-03-04 | 7775.04 | 未披露 | 定期报告 | 2025-03-03 |
| 2025-03-04 | 7733.00 | 未披露 |
更多>>
From December 31, 2023 to December 31, 2024
Issuance of restricted stock
Share-based compensation
Exercise of stock options
|
2024-12-31 |
| 2024-10-31 | 7638.33 | 未披露 | 定期报告 | 2024-10-29 |
| 2024-10-31 | 7602.70 | 未披露 |
更多>>
From July 1, 2024 to September 30, 2024
Issuance of common stock resulting from the exercise of stock options
Issuance of restricted stock
|
2024-09-30 |
| 2024-08-07 | 7593.31 | 未披露 | 定期报告 | 2024-08-05 |
| 2024-08-07 | 7547.30 | 未披露 |
更多>>
From April 1, 2024 to June 30, 2024
Issuance of common stock resulting from the exercise of stock options
Issuance of restricted stock
|
2024-06-30 |
| 2024-05-08 | 7553.88 | 未披露 | 定期报告 | 2024-05-06 |
| 2024-04-25 | 7552.38 | 未披露 | 定期报告 | 2024-04-22 |
| 2024-05-08 | 7515.30 | 未披露 |
更多>>
From January 1, 2024 to March 31, 2024
Issuance of restricted stock
Share-based compensation
|
2024-03-31 |
| 2024-03-06 | 7530.91 | 未披露 | 定期报告 | 2024-03-04 |
| 2024-03-06 | 7498.10 | 未披露 |
更多>>
From December 31,2022 to December 31,2023
Issuance of restricted stock
|
2023-12-31 |
| 2023-11-08 | 7512.44 | 未披露 | 定期报告 | 2023-11-06 |
| 2023-11-08 | 7491.00 | 未披露 |
更多>>
From July 1, 2023 to September 30, 2023
Issuance of restricted stock
|
2023-09-30 |
| 2023-08-09 | 7503.24 | 未披露 | 定期报告 | 2023-08-07 |
| 2023-08-09 | 7485.60 | 未披露 |
更多>>
From April 1, 2023 to June 30, 2023
Issuance of restricted stock
|
2023-06-30 |
| 2023-05-10 | 7496.61 | 未披露 | 定期报告 | 2023-05-08 |
| 2023-04-28 | 7485.12 | 未披露 | 定期报告 | 2023-04-18 |
| 2023-06-22 | 7484.94 | 未披露 |
更多>>
From January 1, 2023 to March 31, 2023
Issuance of restricted stock
|
2023-03-31 |
| 2023-03-08 | 7483.85 | 未披露 | 定期报告 | 2023-03-06 |
| 2023-03-08 | 7456.70 | 未披露 |
更多>>
From December 31, 2021 to December 31, 2022
Issuance of common stock, net of offering costs of $0.4 million
Issuance of restricted stock
|
2022-12-31 |
| 2022-11-02 | 7446.87 | 未披露 | 定期报告 | 2022-10-31 |
| 2022-11-02 | 6816.90 | 未披露 |
更多>>
From July 1, 2022 to September 30, 2022
Issuance of restricted stock
|
2022-09-30 |
| 2022-08-10 | 6834.28 | 未披露 | 定期报告 | 2022-08-08 |
| 2022-08-10 | 6815.50 | 未披露 |
更多>>
From April 1, 2022 to June 30, 2022
Issuance of restricted stock
|
2022-06-30 |
| 2022-04-27 | 6833.46 | 未披露 | 定期报告 | 2022-04-19 |
| 2022-04-27 | 6833.27 | 未披露 | 定期报告 | 2022-04-01 |
| 2022-05-12 | 6814.90 | 未披露 |
更多>>
From January 1, 2022 to March 31, 2022
Issuance of restricted stock
|
2022-03-31 |
| 2022-03-14 | 6830.94 | 未披露 | 定期报告 | 2022-03-09 |
| 2022-03-14 | 6812.60 | 未披露 |
更多>>
From December 31, 2020 to December 31, 2021
Issuance of common stock, net of offering costs of $0.4 million
Exercise of stock options
|
2021-12-31 |
| 2021-11-03 | 6829.15 | 未披露 | 定期报告 | 2021-11-02 |
| 2021-11-03 | 6809.40 | 未披露 |
更多>>
From June 30, 2021 to September 30, 2021
Exercise of stock options
|
2021-09-30 |
| 2021-08-03 | 6819.65 | 未披露 | 定期报告 | 2021-08-02 |
| 2021-08-03 | 6800.90 | 未披露 |
更多>>
From March 31, 2021 to June 30, 2021
Issuance of common stock, net of offering costs of $0.3 million
Exercise of stock options
|
2021-06-30 |
| 2021-04-21 | 6793.25 | 未披露 | 定期报告 | 2021-04-20 |
| 2021-05-06 | 6770.20 | 未披露 |
更多>>
From December 31, 2020 to March 31, 2021
Issuance of common stock, net of offering costs of $0.1 million
Exercise of stock options
|
2021-03-31 |
| 2021-03-23 | 6675.73 | 未披露 | 定期报告 | 2021-03-15 |
| 2021-03-12 | 6673.90 | 未披露 | 定期报告 | 2021-03-05 |
| 2021-03-12 | 6188.10 | 未披露 |
更多>>
from December 31, 2019 to December 31, 2020
Issuance of common stock, net of offering costs of $0.1 million
Exercise of stock options
|
2020-12-31 |
| 2020-11-04 | 6178.77 | 未披露 | 定期报告 | 2020-11-03 |
| 2020-11-04 | 6158.70 | 未披露 |
更多>>
From June 30, 2020 to September 30, 2020
Exercise of stock options
|
2020-09-30 |
| 2020-08-06 | 6162.44 | 未披露 | 定期报告 | 2020-08-05 |
| 2020-08-06 | 6142.10 | 未披露 |
更多>>
from March 31, 2020 to June 30, 2020
Issuance of common stock,net of offering costs of $0.1 million
Exercise of stock options
|
2020-06-30 |
| 2020-05-18 | 6147.79 | 未披露 | 定期报告 | 2020-05-17 |
| 2020-06-12 | 5978.79 | 未披露 |
更多>>
from December 31, 2019 to March 3, 2020
Exercise of stock options
|
2020-03-03 |
| 2020-03-10 | 5956.20 | 未披露 |
更多>>
from December 31, 2018 to December 31, 2019
Issuance of common stock, net of offering costs of $0.2 million
Issuance of common stock for conversion of debt and accrued interest
Exercise of stock options
Exercise of warrants
Share-based compensation
|
2019-12-31 |
| 2019-11-12 | 5957.74 | 未披露 | 定期报告 | 2019-11-11 |
| 2019-11-12 | 5938.30 | 未披露 |
更多>>
from June 30, 2019 to September 30, 2019
Issuance of common stock, net of offering costs of $0.2 million
Issuance of common stock for conversion of debt and accrued interest
Exercise of stock options
Exercise of warrants
|
2019-09-30 |
| 2019-09-12 | 5956.59 | 未披露 | 定期报告 | 2019-09-06 |
| 2019-08-07 | 5571.84 | 未披露 | 定期报告 | 2019-08-06 |
| 2019-08-07 | 5538.40 | 未披露 |
更多>>
From March 31, 2019 to June 30, 2019
Exercise of stock options
|
2019-06-30 |
| 2019-05-09 | 5552.18 | 未披露 | 定期报告 | 2019-05-08 |
| 2019-04-23 | 5551.43 | 未披露 | 定期报告 | 2019-04-22 |
| 2019-05-09 | 5532.10 | 未披露 |
更多>>
from December 31, 2018 to March 31, 2019
Exercise of stock options
Share-based compensation
|
2019-03-31 |
| 2019-03-07 | 5528.59 | 未披露 | 定期报告 | 2019-02-28 |
| 2019-03-07 | 5508.90 | 未披露 |
更多>>
from December 30, 2017 to December 31, 2018
Exercise of stock options
Repurchase of common stock
Vested restricted stock
Share-based compensation
|
2018-12-31 |
| 2018-11-07 | 5510.25 | 未披露 | 定期报告 | 2018-11-06 |
| 2018-11-07 | 5491.90 | 未披露 |
更多>>
From June 30, 2018 to September 30, 2018
Exercise of stock options
|
2018-09-30 |
| 2018-08-09 | 5505.54 | 未披露 | 定期报告 | 2018-08-08 |
| 2018-08-09 | 5468.10 | 未披露 |
更多>>
From December 31, 2017 to June 30, 2018
Exercise of stock options
Repurchase of common stock
Vested restricted stock
|
2018-06-30 |
| 2018-04-27 | 5486.65 | 未披露 | 定期报告 | 2018-04-23 |
| 2018-05-10 | 5468.10 | 未披露 |
更多>>
From December 30, 2017 to March 31, 2018
Exercise of stock options
Repurchase of common stock
Vested restricted stock
|
2018-03-31 |
| 2018-03-15 | 5483.61 | 未披露 | 定期报告 | 2018-03-08 |
| 2018-03-15 | 5469.67 | 未披露 |
更多>>
From December 31, 2016 to December 30, 2017
Issuance of common stock, net of offering costs of $1,420,000
Exercise of stock options
Vested restricted stock
|
2017-12-30 |
| 2017-12-14 | 5383.76 | 未披露 | 定期报告 | 2017-11-20 |
| 2017-11-09 | 4818.73 | 未披露 | 定期报告 | 2017-11-08 |
| 2017-11-09 | 4765.03 | 未披露 |
更多>>
From July 1, 2017 to September 30, 2017
Issuance of common stock,net of offering costs of $103,000
Exercise of stock options
Vested restricted stock
|
2017-09-30 |
| 2017-10-31 | 4805.93 | 未披露 | 定期报告 | 2017-08-21 |
| 2017-08-10 | 4609.39 | 未披露 | 定期报告 | 2017-08-09 |
| 2017-08-10 | 4557.19 | 未披露 |
更多>>
From April 1, 2017 to July 1, 2017
Issuance of common stock,net of offering costs of $1,184,000
Exercise of stock options
Vested restricted stock
|
2017-07-01 |
| 2017-06-09 | 4609.39 | 未披露 | 定期报告 | 2017-05-25 |
| 2017-05-11 | 3979.01 | 未披露 | 定期报告 | 2017-05-10 |
| 2017-05-01 | 3844.21 | 未披露 | 定期报告 | 2017-04-24 |
| 2017-05-11 | 3791.80 | 未披露 |
更多>>
from January 1, 2017 to April 1, 2017
Issuance of common stock associated with the acquisition of Healthspan Research LLC
Exercise of stock options
Vested restricted stock
|
2017-04-01 |
| 2017-03-16 | 3790.77 | 未披露 | 定期报告 | 2017-02-28 |
| 2017-03-16 | 3754.45 | 未披露 |
更多>>
from January 2, 2016 to December 31, 2016
1 for 3 reverse stock split, isssuance due to fractional shares round up
Issuance of common stock, net of offering costs of $33,000
Exercise of stock options
Vested restricted stock
|
2016-12-31 |
| 2016-11-10 | 3790.45 | 未披露 | 定期报告 | 2016-11-09 |
| 2016-11-10 | 3754.32 | 未披露 |
更多>>
From July 2, 2016 to October 1, 2016
Exercise of stock options
Vested restricted stock
|
2016-10-01 |
| 2016-08-11 | 3785.66 | 未披露 | 定期报告 | 2016-08-10 |
| 2016-08-11 | 3748.99 | 未披露 |
更多>>
from April 2, 2016 to July 2, 2016
1 for 3 reverse stock split, isssuance due to fractional shares round up
Issuance of common stock, net of offering costs of $10,000
Exercise of stock options
Vested restricted stock
|
2016-07-02 |
| 2016-05-12 | 3655.45 | 未披露 |
更多>>
On April 13, 2016, the Company effected a 1 for 3 reverse stock split.
|
2016-05-11 |
| 2016-04-25 | 3650.91 | 未披露 |
更多>>
1.The number of shares of our common stock to be outstanding immediately after this offering is based on 109,142,786 shares outstanding
2.On April 13, 2016, the Company effected a 1 for 3 reverse stock split.
|
2016-04-25 |
| 2016-05-12 | 3618.08 | 未披露 |
更多>>
from January 2, 2016 to April 2, 2016
Issuance of common stock, net of offering costs of $20,000
Exercise of stock options
Vested restricted stock
|
2016-04-02 |
| 2016-03-17 | 10801.08 | 未披露 |
更多>>
from January 3, 2015 to January 2, 2016
Issuance of common stock, net of offering costs of $25,000
Exercise of stock options
Vested restricted stock
Share-based compensation
|
2016-01-02 |
From April 1, 2026 to June 30, 2026
Common stock repurchase
Exercise of stock options
Issuance of common stock from ESPP
Issuance of restricted stock
From December 31, 2024 to December 31, 2025
Issuance of restricted stock
Exercise of stock options
Common stock repurchase
From July 1, 2025 to September 30, 2025
Issuance of common stock resulting from the exercise of stock options
From April 1, 2025 to June 30, 2025
Issuance of common stock resulting from the exercise of stock options
Issuance of restricted stock
From January 1, 2025 to March 31, 2025
Issuance of restricted stock
Exercise of stock options
From December 31, 2023 to December 31, 2024
Issuance of restricted stock
Share-based compensation
Exercise of stock options
From July 1, 2024 to September 30, 2024
Issuance of common stock resulting from the exercise of stock options
Issuance of restricted stock
From April 1, 2024 to June 30, 2024
Issuance of common stock resulting from the exercise of stock options
Issuance of restricted stock
From January 1, 2024 to March 31, 2024
Issuance of restricted stock
Share-based compensation
From December 31,2022 to December 31,2023
Issuance of restricted stock
From July 1, 2023 to September 30, 2023
Issuance of restricted stock
From April 1, 2023 to June 30, 2023
Issuance of restricted stock
From January 1, 2023 to March 31, 2023
Issuance of restricted stock
From December 31, 2021 to December 31, 2022
Issuance of common stock, net of offering costs of $0.4 million
Issuance of restricted stock
From July 1, 2022 to September 30, 2022
Issuance of restricted stock
From April 1, 2022 to June 30, 2022
Issuance of restricted stock
From January 1, 2022 to March 31, 2022
Issuance of restricted stock
From December 31, 2020 to December 31, 2021
Issuance of common stock, net of offering costs of $0.4 million
Exercise of stock options
From June 30, 2021 to September 30, 2021
Exercise of stock options
From March 31, 2021 to June 30, 2021
Issuance of common stock, net of offering costs of $0.3 million
Exercise of stock options
From December 31, 2020 to March 31, 2021
Issuance of common stock, net of offering costs of $0.1 million
Exercise of stock options
from December 31, 2019 to December 31, 2020
Issuance of common stock, net of offering costs of $0.1 million
Exercise of stock options
From June 30, 2020 to September 30, 2020
Exercise of stock options
from March 31, 2020 to June 30, 2020
Issuance of common stock,net of offering costs of $0.1 million
Exercise of stock options
from December 31, 2019 to March 3, 2020
Exercise of stock options
from December 31, 2018 to December 31, 2019
Issuance of common stock, net of offering costs of $0.2 million
Issuance of common stock for conversion of debt and accrued interest
Exercise of stock options
Exercise of warrants
Share-based compensation
from June 30, 2019 to September 30, 2019
Issuance of common stock, net of offering costs of $0.2 million
Issuance of common stock for conversion of debt and accrued interest
Exercise of stock options
Exercise of warrants
From March 31, 2019 to June 30, 2019
Exercise of stock options
from December 31, 2018 to March 31, 2019
Exercise of stock options
Share-based compensation
from December 30, 2017 to December 31, 2018
Exercise of stock options
Repurchase of common stock
Vested restricted stock
Share-based compensation
From June 30, 2018 to September 30, 2018
Exercise of stock options
From December 31, 2017 to June 30, 2018
Exercise of stock options
Repurchase of common stock
Vested restricted stock
From December 30, 2017 to March 31, 2018
Exercise of stock options
Repurchase of common stock
Vested restricted stock
From December 31, 2016 to December 30, 2017
Issuance of common stock, net of offering costs of $1,420,000
Exercise of stock options
Vested restricted stock
From July 1, 2017 to September 30, 2017
Issuance of common stock,net of offering costs of $103,000
Exercise of stock options
Vested restricted stock
From April 1, 2017 to July 1, 2017
Issuance of common stock,net of offering costs of $1,184,000
Exercise of stock options
Vested restricted stock
from January 1, 2017 to April 1, 2017
Issuance of common stock associated with the acquisition of Healthspan Research LLC
Exercise of stock options
Vested restricted stock
from January 2, 2016 to December 31, 2016
1 for 3 reverse stock split, isssuance due to fractional shares round up
Issuance of common stock, net of offering costs of $33,000
Exercise of stock options
Vested restricted stock
From July 2, 2016 to October 1, 2016
Exercise of stock options
Vested restricted stock
from April 2, 2016 to July 2, 2016
1 for 3 reverse stock split, isssuance due to fractional shares round up
Issuance of common stock, net of offering costs of $10,000
Exercise of stock options
Vested restricted stock
On April 13, 2016, the Company effected a 1 for 3 reverse stock split.
1.The number of shares of our common stock to be outstanding immediately after this offering is based on 109,142,786 shares outstanding
2.On April 13, 2016, the Company effected a 1 for 3 reverse stock split.
from January 2, 2016 to April 2, 2016
Issuance of common stock, net of offering costs of $20,000
Exercise of stock options
Vested restricted stock
from January 3, 2015 to January 2, 2016
Issuance of common stock, net of offering costs of $25,000
Exercise of stock options
Vested restricted stock
Share-based compensation