股本结构
单位：万股
| 公告日期 | 2026-08-11 | 2026-08-11 | 2026-06-25 | 2026-05-06 | 2026-04-22 | 2026-05-06 |
|---|---|---|---|---|---|---|
| 证券总股本 | 32583.35 | 32530.23 | 31986.10 | 28736.10 | 28734.20 | 28727.69 |
| 普通股本 | 32583.35 | 32530.23 | 31986.10 | 28736.10 | 28734.20 | 28727.69 |
| 优先股 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 |
| 其他 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 |
| 变动日期 | 2026-08-11 | 2026-06-30 | 2026-06-26 | 2026-05-06 | 2026-04-08 | 2026-03-31 |
注释：中概股证券总股本=普通股股本/
存托凭证比例
历史变动
| 公告日期 | 变动后普通股本（万股） | 变动后优先股（万股） | 变动原因 | 变动日期 |
|---|---|---|---|---|
| 2026-08-11 | 32583.35 | 未披露 | 定期报告 | 2026-08-11 |
| 2026-08-11 | 32530.23 | 未披露 |
更多>>
From March 31,2026 to June 30,2026
Issuance of common stock and pre-funded warrants upon closing of underwritten public offering, net of underwriting discounts and commissions, and other offering costs of $14,323
Issuance of common stock upon exercise of stock options, net
Issuance of common stock upon vesting and settlement of restricted stock units, net
|
2026-06-30 |
| 2026-06-25 | 31986.10 | 未披露 |
更多>>
Common stock offered 32,500,001 shares by the company
|
2026-06-26 |
| 2026-05-06 | 28736.10 | 未披露 | 定期报告 | 2026-05-06 |
| 2026-04-22 | 28734.20 | 未披露 | 定期报告 | 2026-04-08 |
| 2026-05-06 | 28727.69 | 未披露 |
更多>>
From December 31,2025 to March 31, 2026
Issuance of common stock upon vesting and settlement of restricted stock units, net
Issuance of stock upon exercise of stock options
Issuance of common stock under ESPP
|
2026-03-31 |
| 2026-03-19 | 28726.99 | 未披露 | 定期报告 | 2026-03-19 |
| 2026-03-19 | 28505.16 | 未披露 |
更多>>
From December 31, 2024 to December 31, 2025
Issuance of common stock and pre-funded warrants upon closing of underwritten public offering, net of underwriting discounts and commissions, and other offering costs of $14,329
Issuance of common stock pursuant to ATM Agreement, net of sales commissions and other offering costs of $1,565
Issuance of common stock upon exercise of pre-funded warrants
Issuance of common stock upon exercise warrants
Issuance of common stock upon vesting and settlement of restricted stock units, net
Issuance of stock upon exercise of stock options
Issuance of common stock under ESPP
|
2025-12-31 |
| 2025-11-04 | 27391.94 | 未披露 | 定期报告 | 2025-11-04 |
| 2025-11-04 | 27391.54 | 未披露 |
更多>>
From June 30, 2025 to September 30, 2025
Issuance of common stock upon vesting and settlement of restricted stock units, net
Issuance of common stock under ESPP
Issuance of common stock upon exercise of stock options
|
2025-09-30 |
| 2025-08-12 | 27279.49 | 未披露 | 定期报告 | 2025-08-12 |
| 2025-08-12 | 27273.01 | 未披露 |
更多>>
From March 31, 2025 to June 30, 2025
Issuance of common stock and pre-funded warrants upon closing of underwritten public offering, net of underwriting discounts and commissions, and other offering costs of $14,323
Issuance of common stock upon exercise of pre-funded warrants
Issuance of common stock upon exercise of stock options, net
Issuance of common stock upon vesting and settlement of restricted stock units, net
|
2025-06-30 |
| 2025-05-29 | 26153.04 | 未披露 |
更多>>
Common stock offered 46,868,687 shares by the company
|
2025-05-30 |
| 2025-05-15 | 21466.17 | 未披露 | 定期报告 | 2025-05-15 |
| 2025-05-15 | 20505.46 | 未披露 |
更多>>
From December 31, 2024 to March 31, 2025
Issuance of common stock upon vesting and settlement of restricted stock units, net
Issuance of common stock under ESPP
|
2025-03-31 |
| 2025-02-26 | 20500.16 | 未披露 | 定期报告 | 2025-02-26 |
| 2024-12-13 | 20494.33 | 未披露 | 定期报告 | 2024-09-30 |
| 2024-08-12 | 20494.33 | 未披露 | 定期报告 | 2024-08-12 |
| 2024-08-12 | 20138.15 | 未披露 |
更多>>
From March 31, 2024 to June 30, 2024
Issuance of common stock and pre-funded warrants upon closing of underwritten public offering, net of underwriting discounts and commissions, and other offering costs of $5,024
Issuance of common stock upon exercise of stock options, net
|
2024-06-30 |
| 2024-06-26 | 20137.94 | 未披露 |
更多>>
Common stock offered 14,361,113 shares by the company
|
2024-06-27 |
| 2024-05-14 | 18701.83 | 未披露 |
更多>>
From December 31, 2023 to March 31, 2024
Issuance of common stock under ESPP
Issuance of common stock upon vesting and settlement of restricted stock units
|
2024-03-31 |
| 2024-03-19 | 18701.83 | 未披露 | 定期报告 | 2024-03-19 |
| 2023-11-14 | 18696.02 | 未披露 |
更多>>
From June 30, 2023 to September 30, 2023
Issuance of common stock upon vesting and settlement of restricted stock units
Issuance of common stock in private placement, net of placement agent commission and offering costs of $7,098
Issuance of common stock under ESPP
|
2023-09-30 |
| 2023-08-30 | 18696.02 | 未披露 | 定期报告 | 2023-08-18 |
| 2023-08-14 | 6446.50 | 未披露 | 定期报告 | 2023-08-14 |
| 2023-08-14 | 6443.26 | 未披露 |
更多>>
From March 31, 2023 to June 30, 2023
Issuance of common stock in private placement, net of offering costs of $40
Issuance of common stock upon vesting and settlement of restricted stock units
|
2023-06-30 |
| 2023-04-05 | 6417.86 | 未披露 | 定期报告 | 2023-04-05 |
| 2023-05-11 | 6347.33 | 未披露 |
更多>>
From December 31, 2022 to March 31, 2023
Issuance of common stock under ESPP
Issuance of common stock upon release of restricted stock units, net
|
2023-03-31 |
| 2023-03-28 | 6347.33 | 未披露 | 定期报告 | 2023-03-28 |
| 2023-03-28 | 6320.75 | 未披露 |
更多>>
From December 31, 2021 to December 31, 2022
Issuance of common stock to Astellas, net of offering costs of $187
Issuance of common stock in a public offering, net of underwriting discount and other offering costs of $2,072
Issuance of common stock, upon vesting and settlement of restricted stock units
Issuance of common stock in an at-the-market offering, net of sales commissions and other offering costs of $392
Issuance of common stock under ESPP
|
2022-12-31 |
| 2022-11-08 | 6244.23 | 未披露 | 定期报告 | 2022-11-08 |
| 2022-10-27 | 5517.59 | 未披露 |
更多>>
Common stock offered 14,000,000 shares by the company
|
2022-10-31 |
| 2022-11-08 | 4117.59 | 未披露 |
更多>>
From June 30, 2022 to September 30, 2022
Issuance of common stock under ESPP
Issuance of common stock upon vesting and settlement of restricted stock units
|
2022-09-30 |
| 2022-08-11 | 4109.32 | 未披露 | 定期报告 | 2022-08-11 |
| 2022-08-11 | 4102.01 | 未披露 |
更多>>
From March 31, 2022 to June 30, 2022
Issuance of common stock, net of sales commissions and other offering costs of $392
Issuance of common stock upon vesting and settlement of restricted stock units
|
2022-06-30 |
| 2022-05-16 | 4054.64 | 未披露 | 定期报告 | 2022-05-16 |
| 2022-04-28 | 4047.39 | 未披露 | 定期报告 | 2022-04-21 |
| 2021-11-10 | 3847.39 | 未披露 |
更多>>
From June 30, 2021 to September 30, 2021
Issuance of common stock, upon vesting and settlement of restricted stock units
|
2021-09-30 |
| 2021-08-16 | 3839.12 | 未披露 |
更多>>
From March 31, 2021 to June 30, 2021
Issuance of common stock upon vesting and settlement of restricted stock units
|
2021-06-30 |
| 2021-05-11 | 3791.75 | 未披露 | 定期报告 | 2021-05-11 |
| 2021-04-29 | 3781.72 | 未披露 | 定期报告 | 2021-04-20 |
| 2020-11-12 | 3776.14 | 未披露 |
更多>>
From June 30, 2020 to September 30, 2020
Issuance of Series A convertible preferred stock, net of offering costs of $165
Conversion of Series A and Series B convertible preferred stock to common stock
Reclassification of preferred stock tranche liability upon issuance of Series A milestone shares
Issuance of Series B convertible preferred stock, net of offering costs of $185
Issuance of shares of common stock in initial public offering, net of offering costs and underwriting discounts and commissions of $15,111
Issuance of restricted stock award
|
2020-09-30 |
| 2020-09-25 | 3581.20 | 未披露 |
更多>>
1.Common stock offered by the company 7,869,566 shares
2.The number of shares of common stock to be outstanding after this offering is based on 27,942,409 shares of common stock outstanding as of June 30, 2020
|
2020-09-24 |
From March 31,2026 to June 30,2026
Issuance of common stock and pre-funded warrants upon closing of underwritten public offering, net of underwriting discounts and commissions, and other offering costs of $14,323
Issuance of common stock upon exercise of stock options, net
Issuance of common stock upon vesting and settlement of restricted stock units, net
Common stock offered 32,500,001 shares by the company
From December 31,2025 to March 31, 2026
Issuance of common stock upon vesting and settlement of restricted stock units, net
Issuance of stock upon exercise of stock options
Issuance of common stock under ESPP
From December 31, 2024 to December 31, 2025
Issuance of common stock and pre-funded warrants upon closing of underwritten public offering, net of underwriting discounts and commissions, and other offering costs of $14,329
Issuance of common stock pursuant to ATM Agreement, net of sales commissions and other offering costs of $1,565
Issuance of common stock upon exercise of pre-funded warrants
Issuance of common stock upon exercise warrants
Issuance of common stock upon vesting and settlement of restricted stock units, net
Issuance of stock upon exercise of stock options
Issuance of common stock under ESPP
From June 30, 2025 to September 30, 2025
Issuance of common stock upon vesting and settlement of restricted stock units, net
Issuance of common stock under ESPP
Issuance of common stock upon exercise of stock options
From March 31, 2025 to June 30, 2025
Issuance of common stock and pre-funded warrants upon closing of underwritten public offering, net of underwriting discounts and commissions, and other offering costs of $14,323
Issuance of common stock upon exercise of pre-funded warrants
Issuance of common stock upon exercise of stock options, net
Issuance of common stock upon vesting and settlement of restricted stock units, net
Common stock offered 46,868,687 shares by the company
From December 31, 2024 to March 31, 2025
Issuance of common stock upon vesting and settlement of restricted stock units, net
Issuance of common stock under ESPP
From March 31, 2024 to June 30, 2024
Issuance of common stock and pre-funded warrants upon closing of underwritten public offering, net of underwriting discounts and commissions, and other offering costs of $5,024
Issuance of common stock upon exercise of stock options, net
Common stock offered 14,361,113 shares by the company
From December 31, 2023 to March 31, 2024
Issuance of common stock under ESPP
Issuance of common stock upon vesting and settlement of restricted stock units
From June 30, 2023 to September 30, 2023
Issuance of common stock upon vesting and settlement of restricted stock units
Issuance of common stock in private placement, net of placement agent commission and offering costs of $7,098
Issuance of common stock under ESPP
From March 31, 2023 to June 30, 2023
Issuance of common stock in private placement, net of offering costs of $40
Issuance of common stock upon vesting and settlement of restricted stock units
From December 31, 2022 to March 31, 2023
Issuance of common stock under ESPP
Issuance of common stock upon release of restricted stock units, net
From December 31, 2021 to December 31, 2022
Issuance of common stock to Astellas, net of offering costs of $187
Issuance of common stock in a public offering, net of underwriting discount and other offering costs of $2,072
Issuance of common stock, upon vesting and settlement of restricted stock units
Issuance of common stock in an at-the-market offering, net of sales commissions and other offering costs of $392
Issuance of common stock under ESPP
Common stock offered 14,000,000 shares by the company
From June 30, 2022 to September 30, 2022
Issuance of common stock under ESPP
Issuance of common stock upon vesting and settlement of restricted stock units
From March 31, 2022 to June 30, 2022
Issuance of common stock, net of sales commissions and other offering costs of $392
Issuance of common stock upon vesting and settlement of restricted stock units
From June 30, 2021 to September 30, 2021
Issuance of common stock, upon vesting and settlement of restricted stock units
From March 31, 2021 to June 30, 2021
Issuance of common stock upon vesting and settlement of restricted stock units
From June 30, 2020 to September 30, 2020
Issuance of Series A convertible preferred stock, net of offering costs of $165
Conversion of Series A and Series B convertible preferred stock to common stock
Reclassification of preferred stock tranche liability upon issuance of Series A milestone shares
Issuance of Series B convertible preferred stock, net of offering costs of $185
Issuance of shares of common stock in initial public offering, net of offering costs and underwriting discounts and commissions of $15,111
Issuance of restricted stock award
1.Common stock offered by the company 7,869,566 shares
2.The number of shares of common stock to be outstanding after this offering is based on 27,942,409 shares of common stock outstanding as of June 30, 2020